Ovarian carcinoma is characterized by heterogeneity at the molecular, cellular and
anatomical levels, both spatially and temporally. This heterogeneity affects response to …

Ovarian carcinoma (OC) is an umbrella term for multiple distinct diseases (histotypes), each
with their own developmental origins, clinical behaviour and molecular profile. Accordingly …

Compared with high-grade serous carcinoma, low-grade serous carcinoma of the ovary or
peritoneum is a less frequent epithelial ovarian cancer type that is poorly sensitive to …

Abstract Background The RAS/RAF/MEK/ERK (MAPK) pathway plays a role in ovarian
carcinogenesis. Low-grade serous ovarian carcinoma (LGSOC) frequently harbors …

Low grade serous ovarian carcinoma (LGSOC) demonstrates unique clinical and molecular
features compared to other ovarian cancer types. The relationship between common …

Low-grade serous carcinoma (LGSC) may develop from serous borderline tumor (SBT)
tissue, where the micropapillary type (mSBT) presents the highest risk for progression. The …

The current paradigm implicates a fallopian tube precursor as the origin of most ovarian high-
grade serous carcinomas (HGSCs). However, a rare subset of HGSCs develop via a distinct …

Background Data on platinum sensitivity of low‐grade serous ovarian carcinoma (LGSOC)
in the upfront setting is lacking, and there is limited and contradictory information on …

Purpose: We present the results of a post hoc tumor tissue analysis from the phase 3
MILO/ENGOT-ov11 study (NCT01849874). Patients and Methods: Mutation/copy-number …

Simple Summary Low-grade serous ovarian cancer is a rare and complex subtype that
usually develops slowly and predominantly affects younger women. Conventional treatment …