The retinal pigment epithelium (RPE) is a highly specialized, unique epithelial cell that
interacts with photoreceptors on its apical side and with Bruch's membrane and the …

Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert
their pro-angiogenic activity by interacting with various endothelial cell surface receptors …

Following an acute phase stimulus, such as infection o1" physical in/ur3; many liver-derived
plasma proteins are increased in concentration. These provide enh: mced protection against …

▪ Abstract C reactive protein, the first innate immunity receptor identified, and serum amyloid
P component are classic short pentraxins produced in the liver. Long pentraxins, including …

Annotated genome sequences, can be used to reconstruct whole-cell metabolic networks,,,.
These metabolic networks can be modelled and analysed (computed) to study complex …

Members of the TGF-β superfamily, which includes TGF-βs, growth differentiation factors,
bone morphogenetic proteins, activins, inhibins, and glial cell line-derived neurotrophic …

Pentraxins are a superfamily of conserved proteins that are characterized by a cyclic
multimeric structure. The classical short pentraxins, C-reactive protein (CRP) and serum …

The innate immune system consists of a cellular and a humoral arm. Pentraxins (eg, the
short pentraxin C reactive protein and the long pentraxin PTX3) are key components of the …

The long pentraxin (PTX) 3 is produced by macrophages and myeloid dendritic cells in
response to Toll-like receptor agonists and represents a nonredundant component of …

Pentraxins are a family of multimeric pattern-recognition proteins highly conserved in
evolution. Based on the primary structure of the subunit, the pentraxins are divided into two …