Beyond their many well-established biological aberrations, solid tumours create an
abnormal physical microenvironment that fuels cancer progression and confers treatment …

Cell surface and intracellular mechanosensors enable cells to perceive different geometric,
topographical, and physical cues. Mechanosensitive ion channels (MICs) localized at the …

In vivo, migrating cells often encounter microenvironments that impose spatial constraints,
leading to cell and nuclear deformation. As confinement‐induced DNA damage has been …

Our understanding of how fluid forces influence cell migration in confining environments
remains limited. By integrating microfluidics with live-cell imaging, we demonstrate that cells …

Although cancer diagnosis and treatment have rapidly advanced in recent decades,
urological malignancies, which have high morbidity and mortality rates, are among the most …

Metastasis accounts for the vast majority of breast cancer-related fatalities. Although the
contribution of genetic and epigenetic modifications to breast cancer progression has been …

3D confinement alters smooth muscle cell responses to chemical and mechanical cues | APL
Bioengineering | AIP Publishing Skip to Main Content Umbrella Alt Text Umbrella Alt Text Close …

Purpose The suboptimal clinical performance of human mesenchymal stem cells (hMSCs)
has raised concerns about their therapeutic potential. One major contributing factor to this …