Clinical Pharmacology of Citrus aurantium and Citrus sinensis for the Treatment of Anxiety

C Mannucci, F Calapai, L Cardia… - Evidence‐Based …, 2018 - Wiley Online Library
Objective. The aim of this review is to analyze preclinical and clinical studies investigating
the anxiety effects of Citrus aurantium or Citrus sinensis essential oils (EOs). Design. The …

p‐Synephrine, ephedrine, p‐octopamine and m‐synephrine: Comparative mechanistic, physiological and pharmacological properties

SJ Stohs, M Shara, SD Ray - Phytotherapy Research, 2020 - Wiley Online Library
Confusion and misunderstanding exist regarding the lack of cardiovascular and other
adverse health effects of p‐synephrine and p‐octopamine relative to ephedrine and m …

Sports drug testing and the athletes' exposome

M Thevis, T Kuuranne, M Fedoruk… - Drug testing and …, 2021 - Wiley Online Library
Similar to the general population, elite athletes are exposed to a complex set of
environmental factors including chemicals and radiation and also biological and physical …

Mass spectrometry-based metabolomics for the discovery of biomarkers of fruit and vegetable intake: citrus fruit as a case study

E Pujos-Guillot, J Hubert, JF Martin… - Journal of proteome …, 2013 - ACS Publications
Elucidation of the relationships between genotype, diet, and health requires accurate dietary
assessment. In intervention and epidemiological studies, dietary assessment usually relies …

The Safety of Citrus aurantium (Bitter Orange) and its Primary Protoalkaloid p‐Synephrine

SJ Stohs, HG Preuss, M Shara - Phytotherapy Research, 2011 - Wiley Online Library
Citrus aurantium (bitter orange) extract and its principal protoalkaloidal constituent p‐
synephrine are widely used in weight loss and weight management as well as in sports …

A Review of the Receptor‐Binding Properties of p‐Synephrine as Related to Its Pharmacological Effects

SJ Stohs, HG Preuss, M Shara - Oxidative Medicine and …, 2011 - Wiley Online Library
Bitter orange (Citrus aurantium) extract and its primary protoalkaloid p‐synephrine are used
widely in weight loss/weight management and sports performance products. Because of …

Simultaneous determination of flavanones, hydroxycinnamic acids and alkaloids in citrus fruits by HPLC-DAD–ESI/MS

D He, Y Shan, Y Wu, G Liu, B Chen, S Yao - Food chemistry, 2011 - Elsevier
A simple and accurate method has been developed to simultaneously separate and
determine 10 bioactive compounds in citrus fruits by high-performance liquid …

Natural sympathomimetic drugs: From pharmacology to toxicology

VM Costa, LGR Grando, E Milandri, J Nardi, P Teixeira… - Biomolecules, 2022 - mdpi.com
Sympathomimetic agents are a group of chemical compounds that are able to activate the
sympathetic nervous system either directly via adrenergic receptors or indirectly by …

Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium

J Mercader, E Wanecq, J Chen, C Carpéné - Journal of physiology and …, 2011 - Springer
The weight loss observed in consumers of extracts of Citrus aurantium (bitter orange) has
been tentatively attributed to the lipolytic and thermogenic effects of the alkaloids abundant …

Determination of selected biogenic amines in Acacia rigidula plant materials and dietary supplements using LC–MS/MS methods

RS Pawar, E Grundel, AR Fardin-Kia… - Journal of pharmaceutical …, 2014 - Elsevier
Extracts of Acacia rigidula leaves are used in weight-loss products sold in vitamin shops and
over the internet with little or no published data about their potential biological effects. In our …