Nanotechnology in cancer diagnosis: progress, challenges and opportunities

Y Zhang, M Li, X Gao, Y Chen, T Liu - Journal of hematology & oncology, 2019 - Springer
In the fight against cancer, early detection is a key factor for successful treatment. However,
the detection of cancer in the early stage has been hindered by the intrinsic limits of …

Liquid biopsy of cancer: a multimodal diagnostic tool in clinical oncology

R Palmirotta, D Lovero, P Cafforio… - … in medical oncology, 2018 - journals.sagepub.com
Over the last decades, the concept of precision medicine has dramatically renewed the field
of medical oncology; the introduction of patient-tailored therapies has significantly improved …

Liquid biopsies: Potential and challenges

I Heidrich, L Ačkar… - … Journal of Cancer, 2021 - Wiley Online Library
The analysis of tumor cells or tumor cell products obtained from blood or other body fluids
(“liquid biopsy”[LB]) provides a broad range of opportunities in the field of oncology. Clinical …

Vimentin: Regulation and pathogenesis

D Paulin, A Lilienbaum, S Kardjian, O Agbulut, Z Li - Biochimie, 2022 - Elsevier
Vimentin, an abundant cytoplasmic intermediate filament protein, is recognized for its
important role in stabilizing intracellular structure. Vimentin has been recognized for its …

Basic principles and recent advances in magnetic cell separation

M Frenea-Robin, J Marchalot - Magnetochemistry, 2022 - mdpi.com
Magnetic cell separation has become a key methodology for the isolation of target cell
populations from biological suspensions, covering a wide spectrum of applications from …

Liquid biopsies

E Lianidou, K Pantel - Genes, Chromosomes and Cancer, 2019 - Wiley Online Library
Liquid biopsy is based on minimally invasive blood tests and has a high potential to
significantly change the therapeutic strategy in cancer patients, providing an extremely …

[HTML][HTML] Tumor circulome in the liquid biopsies for cancer diagnosis and prognosis

J Wu, S Hu, L Zhang, J **n, C Sun, L Wang, K Ding… - Theranostics, 2020 - ncbi.nlm.nih.gov
Liquid biopsy is a convenient, fast, non-invasive and reproducible sampling method that can
dynamically reflect the changes in tumor gene expression profile, and provide a robust basis …

Point-of-care cancer diagnostic devices: From academic research to clinical translation

L Syedmoradi, ML Norton, K Omidfar - Talanta, 2021 - Elsevier
Early and timely diagnosis of cancer plays a decisive role in appropriate treatment and
improves clinical outcomes, improving public health. Significant advances in biosensor …

EMT-associated heterogeneity in circulating tumor cells: sticky friends on the road to metastasis

A Genna, AM Vanwynsberghe, AV Villard, C Pottier… - Cancers, 2020 - mdpi.com
Epithelial–mesenchymal transitions (EMTs) generate hybrid phenotypes with an enhanced
ability to adapt to diverse microenvironments encountered during the metastatic spread …

LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer

T Boulding, RD McCuaig, A Tan, K Hardy, F Wu… - Scientific reports, 2018 - nature.com
Complex regulatory networks control epithelial-to-mesenchymal transition (EMT) but the
underlying epigenetic control is poorly understood. Lysine-specific demethylase 1 (LSD1) is …