The neural basis of homeostatic and anticipatory thirst
Water intake is one of the most basic physiological responses and is essential to sustain life.
The perception of thirst has a critical role in controlling body fluid homeostasis and if …
The perception of thirst has a critical role in controlling body fluid homeostasis and if …
Trpv1
TRPV1 is a well-characterised channel expressed by a subset of peripheral sensory
neurons involved in pain sensation and also at a number of other neuronal and non …
neurons involved in pain sensation and also at a number of other neuronal and non …
TRP ion channels in thermosensation, thermoregulation and metabolism
H Wang, J Siemens - Temperature, 2015 - Taylor & Francis
In humans, the TRP superfamily of cation channels includes 27 related molecules that
respond to a remarkable variety of chemical and physical stimuli. While physiological roles …
respond to a remarkable variety of chemical and physical stimuli. While physiological roles …
TR** to the point of clarity: understanding the function of the complex TRPV4 ion channel
The transient receptor potential vanilloid 4 channel (TRPV4) belongs to the mammalian TRP
superfamily of cation channels. TRPV4 is ubiquitously expressed, activated by a disparate …
superfamily of cation channels. TRPV4 is ubiquitously expressed, activated by a disparate …
TRPV1 in the central nervous system: synaptic plasticity, function, and pharmacological implications
JG Edwards - Capsaicin as a therapeutic molecule, 2014 - Springer
The function of TRPV1 in the peripheral nervous system is increasingly being investigated
for its anti-inflammatory and antinociceptive properties in an effort to find a novel target to …
for its anti-inflammatory and antinociceptive properties in an effort to find a novel target to …
Hypertonicity sensing in organum vasculosum lamina terminalis neurons: a mechanical process involving TRPV1 but not TRPV4
Primary osmosensory neurons in the mouse organum vasculosum lamina terminalis (OVLT)
transduce hypertonicity via the activation of nonselective cation channels that cause …
transduce hypertonicity via the activation of nonselective cation channels that cause …
ΔN-TRPV1: a molecular co-detector of body temperature and osmotic stress
Thirst and antidiuretic hormone secretion occur during hyperthermia or hypertonicity to
preserve body hydration. These vital responses are triggered when hypothalamic …
preserve body hydration. These vital responses are triggered when hypothalamic …
60 YEARS OF NEUROENDOCRINOLOGY: The posterior pituitary, from Geoffrey Harris to our present understanding
Geoffrey Harris pioneered our understanding of the posterior pituitary, mainly with
experiments that involved the electrical stimulation of the supraoptico-hypophysial tract. In …
experiments that involved the electrical stimulation of the supraoptico-hypophysial tract. In …
TRPA1 and TRPV4 activation in human odontoblasts stimulates ATP release
O Egbuniwe, S Grover, AK Duggal… - Journal of dental …, 2014 - journals.sagepub.com
The mechanism of pain in dentine hypersensitivity is poorly understood but proposed to
result from the activation of dental sensory neurons in response to dentinal fluid movements …
result from the activation of dental sensory neurons in response to dentinal fluid movements …
Polymodal TRPV1 and TRPV4 sensors colocalize but do not functionally interact in a subpopulation of mouse retinal ganglion cells
M Lakk, D Young, JM Baumann, AO Jo… - Frontiers in cellular …, 2018 - frontiersin.org
Retinal ganglion cells (RGCs) are projection neurons that transmit the visual signal from the
retina to the brain. Their excitability and survival can be strongly influenced by mechanical …
retina to the brain. Their excitability and survival can be strongly influenced by mechanical …