A novel nanohybrid for cancer theranostics: folate sensitized Fe 2 O 3 nanoparticles for colorectal cancer diagnosis and photodynamic therapy

R Nandi, S Mishra, TK Maji, K Manna, P Kar… - Journal of Materials …, 2017 - pubs.rsc.org
Organic–inorganic nanohybrids are becoming popular for their potential biological
applications, including diagnosis and treatment of cancerous cells. The motive of this study …

Unraveling the role of monoolein in fluidity and dynamical response of a mixed cationic lipid bilayer

P Singh, VK Sharma, S Singha, V García Sakai… - Langmuir, 2019 - ACS Publications
The maintenance of cell membrane fluidity is of critical importance for various cellular
functions. At lower temperatures when membrane fluidity decreases, plants and …

Selective and fast responsive sensitized micelle for detection of fluoride level in drinking water

A Halder, S Singh, A Adhikari, P Singh… - ACS Sustainable …, 2019 - ACS Publications
Consumption of excess fluorides through drinking water and its adverse effects on human
health is of global concern. Given that people from at least 25 countries are suffering from …

Ultrafast spectroscopy on DNA-cleavage by endonuclease in molecular crowding

P Singh, S Choudhury, S Dutta, A Adhikari… - International journal of …, 2017 - Elsevier
The jam-packed intracellular environments differ the activity of a biological macromolecule
from that in laboratory environments (in vitro) through a number of mechanisms called …

Host assisted molecular recognition by human serum albumin: Study of molecular recognition controlled protein/drug mimic binding in a microfluidic channel

D Mukherjee, P Singh, S Singh, DS Roy… - International Journal of …, 2021 - Elsevier
Human serum albumin (HSA) plays a pivotal role in drug release from its delivery vehicles
such as cyclodextrins (CDs) by binding to the drugs. Here molecular recognition and binding …

Elucidating Electronic Structure Variations in Nucleic Acid-Protein Complexes Involved in Transcription Regulation Using a Tight-Binding Approach

L Du, C Liu - bioRxiv, 2024 - biorxiv.org
Transcription factor (TF) are proteins that regulates the transcription of genetic information
from DNA to messenger RNA by binding to a specific DNA sequence. Nucleic acid-protein …

Conformational selection underpins recognition of multiple DNA sequences by proteins and consequent functional actions

G Naiya, P Raha, MK Mondal, U Pal, R Saha… - Physical Chemistry …, 2016 - pubs.rsc.org
Recognition of multiple functional DNA sequences by a DNA-binding protein occurs widely
in nature. The physico-chemical basis of this phenomenon is not well-understood. The E …

Ultrafast differential flexibility of Cro-protein binding domains of two operator DNAs with different sequences

S Choudhury, B Ghosh, P Singh, R Ghosh… - Physical Chemistry …, 2016 - pubs.rsc.org
The nature of the interface of specific protein–DNA complexes has attracted immense
interest in contemporary molecular biology. Although extensive studies on the role of …

Modulation of Kinetic Pathways of Enzyme–Substrate Interaction in a Microfluidic Channel: Nanoscopic Water Dynamics as a Switch

P Singh, D Mukherjee, S Singha… - … –A European Journal, 2019 - Wiley Online Library
Enzyme‐mediated catalysis is attributed to enzyme–substrate interactions, with models such
as “induced fit” and “conformational selection” emphasizing the role of protein …

Ultrafast dynamics-driven biomolecular recognition where fast activities dictate slow events

P Singh, D Bagchi, SK Pal - Journal of Biosciences, 2018 - Springer
In general, biological macromolecules require significant dynamical freedom to carry out
their different functions, including signal transduction, metabolism, catalysis and gene …