Remodeling of the myocardium is the major mechanism for disability and death in prevalent
cardiovascular diseases such as hypertension, heart failure and myocardial infarction (MI). It …

It is now well known that congestive heart failure (CHF) is invariably associated with cardiac
hypertrophy, and changes in the shape and size of cardiomyocytes (cardiac remodeling) are …

Aims Hypoxia is a common stress to the foetus and results in increased cardiac vulnerability
to adult ischaemic injury. This study tested the hypothesis that foetal hypoxia causes …

Background—Elderly patients with reperfused ST-segment-elevation myocardial infarction
are at increased risk for left ventricular remodeling. Extracellular matrix damage has been …

Recent studies demonstrated that the cardiac calpain system is activated during ischaemic
events and is involved in cardiomyocyte injury. The aim of this study was to investigate the …

Previous studies have shown that female offspring are resistant to fetal stress-induced
programming of ischemic-sensitive phenotype in the heart; however, the mechanisms …

OBJECTIVES This study investigated the role of angiotensin receptor subtype 1 (AT1) and
angiotensin receptor subtype 2 (AT2) in the regulation of Na+-H+ exchanger (NHE) and Na+ …

In this study, we demonstrate the use of proteomics to detect regional differences in protein
levels between the reperfused ischemic zone (IZ) and the nonischemic zone (NIZ) of dog …

Myocardial ischemia, ischemia-reperfusion (I/R) and myocardial infarction (MI) are major
causes of morbidity and mortality due to ischemic heart disease in developed and …

To determine whether cardioprotection after chronic angiotensin II (Ang II) type 1 (AT1)
receptor blockade involves Ang II type 2 (AT2) receptor expression and protein kinase C-ε …