Homeostasis of glucose and lipid in non-alcoholic fatty liver disease

HW Chao, SW Chao, H Lin, HC Ku… - International journal of …, 2019 - mdpi.com
Industrialized society-caused dysregular human behaviors and activities such as
overworking, excessive dietary intake, and sleep deprivation lead to perturbations in the …

Griseofulvin: an updated overview of old and current knowledge

P Aris, Y Wei, M Mohamadzadeh, X **a - Molecules, 2022 - mdpi.com
Griseofulvin is an antifungal polyketide metabolite produced mainly by ascomycetes. Since it
was commercially introduced in 1959, griseofulvin has been used in treating dermatophyte …

Proteomic analysis reveals key differences between squamous cell carcinomas and adenocarcinomas across multiple tissues

Q Song, Y Yang, D Jiang, Z Qin, C Xu, H Wang… - Nature …, 2022 - nature.com
Squamous cell carcinoma (SCC) and adenocarcinoma (AC) are two main histological
subtypes of solid cancer; however, SCCs are derived from different organs with similar …

KRT18 is correlated with the malignant status and acts as an oncogene in colorectal cancer

J Zhang, S Hu, Y Li - Bioscience reports, 2019 - portlandpress.com
Abstract Keratin 18 (KRT18) has been suggested to be overexpressed in most types of
human tumor, but the expression pattern of KRT18 in colorectal cancer (CRC) remained …

Single cell-spatial transcriptomics and bulk multi-omics analysis of heterogeneity and ecosystems in hepatocellular carcinoma

J Ye, Y Lin, Z Liao, X Gao, C Lu, L Lu, J Huang… - NPJ Precision …, 2024 - nature.com
This study profiled global single cell-spatial-bulk transcriptome landscapes of hepatocellular
carcinoma (HCC) ecosystem from six HCC cases and a non-carcinoma liver control donor …

Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones

D Karademir, V Todorova, LJA Ebner, M Samardzija… - BMC biology, 2022 - Springer
Background In inherited retinal disorders such as retinitis pigmentosa (RP), rod
photoreceptor-specific mutations cause primary rod degeneration that is followed by …

High KRT8 Expression Independently Predicts Poor Prognosis for Lung Adenocarcinoma Patients

L **e, Y Dang, J Guo, X Sun, T **e, L Zhang, Z Yan… - Genes, 2019 - mdpi.com
Keratin 8 (KRT8), a type II basic intermediate filament (IF) protein, is essential for the
development and metastasis of various cancers. In this study, by analyzing RNA-seq data …

KRT18 modulates alternative splicing of genes involved in proliferation and apoptosis processes in both gastric cancer cells and clinical samples

B Chen, X Xu, D Lin, X Chen, Y Xu, X Liu… - Frontiers in genetics, 2021 - frontiersin.org
Keratin 18 (KRT18), one of the most abundant keratins in epithelial and endothelial cells,
has been reported to be aberrantly expressed in many malignancies and extensively …

An isoform-resolution transcriptomic atlas of colorectal cancer from long-read single-cell sequencing

Z Li, B Zhang, JJ Chan, H Tabatabaeian, QY Tong… - Cell Genomics, 2024 - cell.com
Colorectal cancer (CRC) ranks as the second leading cause of cancer deaths globally. In
recent years, short-read single-cell RNA sequencing (scRNA-seq) has been instrumental in …

Effects of essential oil of Origanum onites and its major component carvacrol on the expression of toxicity pathway genes in HepG2 cells

Ö Tomsuk, V Kuete, H Sivas, M Kürkçüoğlu - … medicine and therapies, 2024 - Springer
Background Origanum species have been used in various commercial constructions as a
remedy against burns and wounds, agriculture, alcoholic drinks, fragrance, and flavoring …