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Rapid and efficient generation of myelinating human oligodendrocytes in organoids
Human stem cell derived brain organoids are increasingly gaining attention as an ideal
model system for investigating neurological diseases, particularly those that involve …
model system for investigating neurological diseases, particularly those that involve …
Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2
Why individuals with Down syndrome (DS) are more susceptible to SARS-CoV-2–induced
neuropathology remains elusive. Choroid plexus (ChP) plays critical roles in barrier function …
neuropathology remains elusive. Choroid plexus (ChP) plays critical roles in barrier function …
Klotho inhibits neuronal senescence in human brain organoids
Aging is a major risk factor for many neurodegenerative diseases. Klotho (KL) is a
glycosylated transmembrane protein that is expressed in the choroid plexus and neurons of …
glycosylated transmembrane protein that is expressed in the choroid plexus and neurons of …
Accelerating cell migration along radially aligned nanofibers through the addition of electrosprayed nanoparticles in a radial density gradient
J Xue, T Wu, J Qiu, Y ** mouse spinal cord
Aims During vertebrate development, the posterior end of the embryo progressively
elongates in a head-to-tail direction to form the body plan. Recent lineage tracing …
elongates in a head-to-tail direction to form the body plan. Recent lineage tracing …
Completion of neural crest cell production and emigration is regulated by retinoic-acid-dependent inhibition of BMP signaling
D Rekler, C Kalcheim - Elife, 2022 - elifesciences.org
Production and emigration of neural crest cells is a transient process followed by the
emergence of the definitive roof plate. The mechanisms regulating the end of neural crest …
emergence of the definitive roof plate. The mechanisms regulating the end of neural crest …
Neural epidermal growth factor-like like protein 2 is expressed in human oligodendroglial cell types
Neural epidermal growth factor-like like 2 (NELL2) is a cytoplasmic and secreted
glycosylated protein with six epidermal growth factor-like domains. In animal models, NELL2 …
glycosylated protein with six epidermal growth factor-like domains. In animal models, NELL2 …
The role of Wnt signaling in the development of the epiblast and axial progenitors
RE Schnirman, SJ Kuo, RC Kelly… - Current topics in …, 2023 - Elsevier
Understanding how the body plan is established during embryogenesis remains a
fundamental biological question. The Wnt/β-catenin signaling pathway plays a crucial and …
fundamental biological question. The Wnt/β-catenin signaling pathway plays a crucial and …
[HTML][HTML] Embryonal neuromesodermal progenitors for caudal central nervous system and tissue development
Neuromesodermal progenitors (NMPs) constitute a bipotent cell population that generates a
wide variety of trunk cell and tissue types during embryonic development. Derivatives of …
wide variety of trunk cell and tissue types during embryonic development. Derivatives of …
[HTML][HTML] Human induced pluripotent stem cells generated from epilepsy patients for use as in vitro models for drug screening
In this paper, we describe the generation and validation of human induced pluripotent stem
cell (hiPSC) lines from peripheral blood mononuclear cells (PBMCs) from 6 epilepsy …
cell (hiPSC) lines from peripheral blood mononuclear cells (PBMCs) from 6 epilepsy …