Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance

CJ Kim, R Romero, P Chaemsaithong… - American journal of …, 2015 - Elsevier
Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …

Immunobiology of acute chorioamnionitis

M Cappelletti, P Presicce, SG Kallapur - Frontiers in immunology, 2020 - frontiersin.org
Acute chorioamnionitis is characterized by neutrophilic infiltration and inflammation at the
maternal fetal interface. It is a relatively common complication of pregnancy and can have …

Intermittent hypoxic episodes in preterm infants: do they matter?

RJ Martin, K Wang, Ö Köroğlu, J Di Fiore, P Kc - Neonatology, 2011 - karger.com
Intermittent hypoxic episodes are typically a consequence of immature respiratory control
and remain a troublesome challenge for the neonatologist. Furthermore, their frequency and …

A point of care test for interleukin-6 in amniotic fluid in preterm prelabor rupture of membranes: a step toward the early treatment of acute intra-amniotic inflammation …

P Chaemsaithong, R Romero… - The journal of …, 2016 - Taylor & Francis
Objective: Preterm prelabor rupture of membranes (preterm PROM) accounts for 30–40% of
spontaneous preterm deliveries and thus is a major contributor to perinatal morbidity and …

Interface‐Stabilized Fiber Sensor for Real‐Time Monitoring of Amniotic Fluid During Pregnancy

Q Li, D Li, J Lu, K Zou, L Wang, Y Jiao… - Advanced …, 2024 - Wiley Online Library
Diseases in pregnancy endanger millions of fetuses worldwide every year. The onset of
these diseases can be early warned by the dynamic abnormalities of biochemicals in …

Inflammatory response in acute chorioamnionitis

RW Redline - Seminars in Fetal and Neonatal Medicine, 2012 - Elsevier
Acute chorioamnionitis is the principal antecedent of premature birth and an important
contributor to specific neonatal and other complications that may extend throughout …

Antenatal suppression of IL-1 protects against inflammation-induced fetal injury and improves neonatal and developmental outcomes in mice

M Nadeau-Vallée, PY Chin, L Belarbi… - The Journal of …, 2017 - journals.aai.org
MN-V, SP, SAR, SG, and SC designed the research studies; MN-V., P.-YC, LB, M.-ÈB, SP,
MHB, AM, AB-R., DJS, AL-M., XH, A. Boudreault, AC, IB, and SG conducted experiments; …

Landscape of preterm birth therapeutics and a path forward

BS Coler, O Shynlova, A Boros-Rausch, S Lye… - Journal of Clinical …, 2021 - mdpi.com
Preterm birth (PTB) remains the leading cause of infant morbidity and mortality. Despite 50
years of research, therapeutic options are limited and many lack clear efficacy. Tocolytic …

[HTML][HTML] The fetal inflammatory response syndrome: the origins of a concept, pathophysiology, diagnosis, and obstetrical implications

E Jung, R Romero, L Yeo, R Diaz-Primera… - Seminars in Fetal and …, 2020 - Elsevier
The fetus can deploy a local or systemic inflammatory response when exposed to
microorganisms or, alternatively, to non-infection-related stimuli (eg, danger signals or …

[HTML][HTML] IL-1 signaling mediates intrauterine inflammation and chorio-decidua neutrophil recruitment and activation

P Presicce, CW Park, P Senthamaraikannan… - JCI insight, 2018 - ncbi.nlm.nih.gov
Neutrophil infiltration of the chorioamnion-decidua tissue at the maternal-fetal interface
(chorioamnionitis) is a leading cause of prematurity, fetal inflammation, and perinatal …