The heavy metals lead (Pb), mercury (Hg), and cadmium (Cd) are ubiquitous environmental
pollutants and are known to exert severe adverse impacts on the nervous system even at …

The global population is expected to have about 131.5 million people living with Alzheimer's
disease (AD) and other dementias by 2050, posing a severe health crisis. Dementia is a …

Importance Diagnostic incidence data for syndromes associated with frontotemporal lobar
degeneration (FTLD) in multinational studies are urgent in light of upcoming therapeutic …

Approximately 30% of elderly adults are cognitively unimpaired at time of death despite the
presence of Alzheimer's disease neuropathology at autopsy. Studying individuals who are …

Frontotemporal dementia encompasses a group of clinical syndromes defined
pathologically by degeneration of the frontal and temporal lobes. Historically, these …

Introduction Progranulin (PGRN) is a secreted glycoprotein, the expression of which is
linked to several neurodegenerative diseases. Although its specific function is still unclear …

Introduction Frontotemporal dementia (FTD) encompasses a wide spectrum of genetic,
clinical, and histological findings. Sex is emerging as a potential biological variable …

This cross-sectional study aimed to identify caregiver burden and its determinants in the
informal caregivers of older patients with dementia (PWDs) aged≥ 60 years in Java …

Background: While the gender/sex differences in neuropsychiatric symptoms in dementia
population are well described, gender/sex differences in mild behavioral impairment (MBI) in …

Background Neuropsychiatric symptoms (NPS) are a core feature of most
neurodegenerative and cerebrovascular diseases. White matter hyperintensities and brain …