The power of ion mobility-mass spectrometry for structural characterization and the study of conformational dynamics

F Lanucara, SW Holman, CJ Gray, CE Eyers - Nature chemistry, 2014 - nature.com
Mass spectrometry is a vital tool for molecular characterization, and the allied technique of
ion mobility is enhancing many areas of (bio) chemical analysis. Strong synergy arises …

Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research

JL Norris, RM Caprioli - Chemical reviews, 2013 - ACS Publications
Human beings are adept at discerning relevant information from complex systems by
processing visual information. Similarly, as scientists labor to understand the fundamental …

[BOOK][B] Ion mobility spectrometry

GA Eiceman, Z Karpas - 2005 - taylorfrancis.com
Key Developments for Faster, More Precise Detection Capabilities Driven by the demand for
the rapid and advanced detection of explosives, chemical and biological warfare agents …

[HTML][HTML] Advanced MALDI mass spectrometry imaging in pharmaceutical research and drug development

S Schulz, M Becker, MR Groseclose, S Schadt… - Current opinion in …, 2019 - Elsevier
Highlights•Ideal mass spectrometer for MALDI MSI would satisfy the '4S-criteria for
performance'(speed, specificity, spatial resolution and sensitivity).•Quantification MALDI MSI …

Mass spectrometric imaging for biomedical tissue analysis

K Chughtai, RMA Heeren - Chemical reviews, 2010 - ACS Publications
A mass spectrometer is described as the smallest weighing scale ever used in the world. 1
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …

[HTML][HTML] Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution

PD Piehowski, Y Zhu, LM Bramer, KG Stratton… - Nature …, 2020 - nature.com
Biological tissues exhibit complex spatial heterogeneity that directs the functions of
multicellular organisms. Quantifying protein expression is essential for elucidating …

Nano-DESI mass spectrometry imaging of proteoforms in biological tissues with high spatial resolution

M Yang, D Unsihuay, H Hu, F Nguele Meke… - Analytical …, 2023 - ACS Publications
Mass spectrometry imaging (MSI) is a powerful tool for label-free map** of the spatial
distribution of proteins in biological tissues. We have previously demonstrated imaging of …

Mass spectrometry imaging for plant biology: a review

BA Boughton, D Thinagaran, D Sarabia, A Bacic… - Phytochemistry …, 2016 - Springer
Mass spectrometry imaging (MSI) is a develo** technique to measure the spatio-temporal
distribution of many biomolecules in tissues. Over the preceding decade, MSI has been …

Mass spectrometry imaging with high resolution in mass and space

A Römpp, B Spengler - Histochemistry and cell biology, 2013 - Springer
Mass spectrometry (MS) imaging links molecular information and the spatial distribution of
analytes within a sample. In contrast to most histochemical techniques, mass spectrometry …

MALDI imaging of lipid biochemistry in tissues by mass spectrometry

KA Zemski Berry, JA Hankin, RM Barkley… - Chemical …, 2011 - ACS Publications
As a result of recent advances, remarkable images revealing the distribution of complex
lipids in tissues are now generated by matrix-assisted laser desorption/ionization imaging …