Maintenance of a homeostatic body core temperature is a critical brain function
accomplished by a central neural network. This orchestrates a complex behavioral and …

Thermogenesis, the production of heat energy, is the specific, neurally regulated, metabolic
function of brown adipose tissue (BAT) and contributes to the maintenance of body …

The mechanism by which pharmacologic administration of the hormone FGF21 increases
energy expenditure to cause weight loss in obese animals is unknown. Here we report that …

Central neural circuits orchestrate a homeostatic repertoire to maintain body temperature
during environmental temperature challenges and to alter body temperature during the …

Brown and beige adipocytes arise from distinct developmental origins. Brown adipose tissue
(BAT) develops embryonically from precursors that also give to skeletal muscle. Beige fat …

Thermogenesis, the production of heat energy, is an essential component of the homeostatic
repertoire to maintain body temperature in mammals and birds during the challenge of low …

Body weight is determined by a balance between food intake and energy expenditure.
Multiple neural circuits in the brain have evolved to process information about food, food …

Brown adipose tissue (BAT) is a specialized organ responsible for thermogenesis, a process
required for maintaining body temperature. BAT is regulated by the sympathetic nervous …

Thermogenesis, the production of heat energy, is an essential component of the homeostatic
repertoire to maintain body temperature during the challenge of low environmental …

Stress activates multiple neural and endocrine systems to allow an animal to respond to and
survive in a threatening environment. The corticotropin-releasing factor system is a primary …