[HTML][HTML] Cancer overdiagnosis: a challenge in the era of screening

BK Dunn, S Woloshin, H **e, BS Kramer - Journal of the National Cancer …, 2022 - Elsevier
Abstract “Screening” is a search for preclinical, asymptomatic disease, including cancer.
Widespread cancer screening has led to large increases in early-stage cancers and pre …

Principles of diagnostic stewardship: a practical guide from the Society for Healthcare Epidemiology of America Diagnostic Stewardship Task Force

V Fabre, A Davis, DJ Diekema, B Granwehr… - Infection Control & …, 2023 - cambridge.org
We provide an overview of diagnostic stewardship with key concepts that include the
diagnostic pathway and the multiple points where interventions can be implemented …

Discovery through clinical sequencing in oncology

MTA Donoghue, AM Schram, DM Hyman, BS Taylor - Nature cancer, 2020 - nature.com
The molecular characterization of tumors now informs clinical cancer care for many patients.
This advent of molecular oncology has been driven by the expanding number of therapeutic …

Association of inappropriate outpatient pediatric antibiotic prescriptions with adverse drug events and health care expenditures

AM Butler, DS Brown, MJ Durkin… - JAMA network …, 2022 - jamanetwork.com
Importance Nonguideline antibiotic prescribing for the treatment of pediatric infections is
common, but the consequences of inappropriate antibiotics are not well described. Objective …

Incidental coronary artery calcium: opportunistic screening of previous nongated chest computed tomography scans to improve statin rates (NOTIFY-1 project)

AT Sandhu, F Rodriguez, S Ngo, BN Patel… - Circulation, 2023 - Am Heart Assoc
Background: Coronary artery calcium (CAC) can be identified on nongated chest computed
tomography (CT) scans, but this finding is not consistently incorporated into care. A deep …

Low-value care at the actionable level of individual health systems

I Ganguli, NE Morden, CWW Yang… - JAMA Internal …, 2021 - jamanetwork.com
Importance Low-value health care remains prevalent in the US despite decades of work to
measure and reduce such care. Efforts have been only modestly effective in part because …

[HTML][HTML] Do not routinely offer imaging for uncomplicated low back pain

AM Hall, K Aubrey-Bassler, B Thorne, CG Maher - bmj, 2021 - bmj.com
Do not routinely offer imaging for uncomplicated low back pain | The BMJ Skip to main content
Intended for healthcare professionals Access provided by Google Indexer Subscribe My …

Targeted detection of cancer at the cellular level during biopsy by near-infrared confocal laser endomicroscopy

GT Kennedy, FS Azari, E Bernstein, B Nadeem… - Nature …, 2022 - nature.com
Suspicious nodules detected by radiography are often investigated by biopsy, but the
diagnostic yield of biopsies of small nodules is poor. Here we report a method—NIR-nCLE …

Factors associated with physician tolerance of uncertainty: an observational study

AS Begin, M Hidrue, S Lehrhoff… - Journal of general …, 2022 - Springer
Background Physicians need to learn and work amidst a plethora of uncertainties, which
may drive burnout. Understanding differences in tolerance of uncertainty is an important …

Incidental findings and low-value care

MS Davenport - American Journal of Roentgenology, 2023 - Am Roentgen Ray Soc
Incidental imaging findings are common and analogous to the results of screening tests
when screening is performed of unselected, low-risk patients. Approximately 15–30% of all …