Background Researchers have suggested that omega‐3 polyunsaturated fatty acids from
oily fish (long‐chain omega‐3 (LCn3), including eicosapentaenoic acid (EPA) and …

HMG-CoA reductase inhibitors (statins) are a widely used class of drug, and like all
medications, have potential for adverse effects (AEs). Here we review the statin AE literature …

Mitochondrial dysfunctions have been implicated in the pathophysiology of several age-
related diseases including age-related macular degeneration (AMD), a progressive …

The mitochondrion is a vital intracellular organelle for retinal cell function and survival. There
is growing confirmation to support an association between mitochondrial dysfunction and a …

Objective To evaluate the efficacy of docosahexaenoic acid (DHA)–enriched oral
supplementation in preventing exudative age-related macular degeneration (AMD). Design …

Background: Omega-3 polyunsaturated fatty acids (n-3 PUFA) are structural components of
the brain and are indispensable for neuronal membrane synthesis. Along with decline in …

Age-related macular degeneration (AMD) is an ever-increasing, insidious disease which
reduces the quality of life of millions of elderly people around the world. AMD is …

As major components of neuronal membranes, omega-3 polyunsaturated acids (n-3 PUFA)
exhibit a wide range of regulatory functions, modulating from synaptic plasticity to …

Abstract Coenzyme Q10 (CoQ10) is a mitochondrial-targeted antioxidant with known
neuroprotective activity. Its ocular effects when co-solubilised with α–tocopherol …

Age-related macular degeneration, the leading cause of irreversible visual loss among older
adults in developed countries, is a chronic, multifactorial, and progressive disease with the …