Malignant brain tumours are complex ecosystems containing neoplastic and stromal
components that generate adaptive and evolutionarily driven aberrant tissues in the central …

Brain tumors remain one of the most difficult tumors to treat and, depending on the
diagnosis, have a poor prognosis. Of brain tumors, glioblastoma (GBM) is the most common …

Glioblastoma (GBM) is the most common malignant adult brain cancer with no curative
treatment strategy. A significant hurdle in GBM treatment is effective therapeutic delivery to …

Simple Summary This paper summarizes the crosstalk between tumor/non-tumor cells and
other elements of the glioblastoma (GB) microenvironment. In tumor pathology, glial cells …

Because of the limited treatment strategy of gliomas, the key of diagnosis and treatment is
finding new molecular biomarkers. Here, we explored the potential of β2-microglobulin …

Glioblastoma ranks among the most aggressive and lethal of all human cancers. Self-
renewing, highly tumorigenic glioblastoma stem cells (GSCs) contribute to therapeutic …

Gliomas develop in unique and complicated environments that nourish tumor cells. The
tumor microenvironment (TME) of gliomas comprises heterogeneous cells, including brain …

The most prevalent and aggressive type of brain cancer, namely, glioblastoma (GBM), is
characterized by intra-and inter-tumor heterogeneity and strong spreading capacity, which …

Glioblastoma the most aggressive form of brain cancer, comprises a complex mixture of
tumor cells and nonmalignant stromal cells, including neurons, astrocytes, microglia …

Angiogenesis is a key process in various physiological and pathological conditions in the
nervous system and in the retina during postnatal life. Although an increasing number of …