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Roles of axon guidance molecules in neuronal wiring in the develo** spinal cord
A Chédotal - Nature Reviews Neuroscience, 2019 - nature.com
The spinal cord receives, relays and processes sensory information from the periphery and
integrates this information with descending inputs from supraspinal centres to elicit precise …
integrates this information with descending inputs from supraspinal centres to elicit precise …
New genetics in congenital hypothyroidism
A Stoupa, D Kariyawasam, M Muzza, T de Filippis… - Endocrine, 2021 - Springer
Introduction Congenital hypothyroidism (CH) is the most frequent neonatal endocrine
disorder and one of the most common preventable forms of mental retardation worldwide …
disorder and one of the most common preventable forms of mental retardation worldwide …
Genetics of mirror movements identifies a multifunctional complex required for Netrin-1 guidance and lateralization of motor control
S Schlienger, PT Yam, N Balekoglu, H Ducuing… - Science …, 2023 - science.org
Mirror movements (MM) disorder is characterized by involuntary movements on one side of
the body that mirror intentional movements on the opposite side. We performed genetic …
the body that mirror intentional movements on the opposite side. We performed genetic …
Mitochondrial dysfunction as a target in spinal cord injury: intimate correlation between pathological processes and therapeutic approaches
J Schmidt, HR Quintá - Neural regeneration research, 2023 - journals.lww.com
Traumatic spinal cord injuries interrupt the connection of all axonal projections with their
neuronal targets below and above the lesion site. This interruption results in either …
neuronal targets below and above the lesion site. This interruption results in either …
Neurogenesis, neuronal migration, and axon guidance
A Accogli, N Addour-Boudrahem, M Srour - Handbook of clinical neurology, 2020 - Elsevier
Abstract Development of the central nervous system (CNS) is a complex, dynamic process
that involves a precisely orchestrated sequence of genetic, environmental, biochemical, and …
that involves a precisely orchestrated sequence of genetic, environmental, biochemical, and …
Insights from the neural guidance factor Netrin-1 into neurodegeneration and other diseases
M Cai, Q Zheng, Y Chen, S Liu, H Zhu… - Frontiers in Molecular …, 2024 - frontiersin.org
Netrin-1 was initially discovered as a neuronal growth cue for axonal guidance, and its
functions have later been identified in inflammation, tumorigenesis, neurodegeneration, and …
functions have later been identified in inflammation, tumorigenesis, neurodegeneration, and …
Involvement of netrins and their receptors in neuronal migration in the cerebral cortex
In mammals, excitatory cortical neurons develop from the proliferative epithelium and
progenitor cells in the ventricular zone and subventricular zone, and migrate radially to the …
progenitor cells in the ventricular zone and subventricular zone, and migrate radially to the …
DCC mutation update: Congenital mirror movements, isolated agenesis of the corpus callosum, and developmental split brain syndrome
The deleted in colorectal cancer (DCC) gene encodes the netrin‐1 (NTN1) receptor DCC, a
transmembrane protein required for the guidance of commissural axons. Germline DCC …
transmembrane protein required for the guidance of commissural axons. Germline DCC …
Genetics of congenital hypothyroidism: Modern concepts
A Stoupa, D Kariyawasam, M Polak, A Carré - Pediatric Investigation, 2022 - mednexus.org
Congenital hypothyroidism (CH) is the most common neonatal endocrine disorder and one
of the most common preventable causes of intellectual disability in the world. CH may be …
of the most common preventable causes of intellectual disability in the world. CH may be …
Commissural axon guidance in the develo** spinal cord: from Cajal to the present day
During neuronal development, the formation of neural circuits requires develo** axons to
traverse a diverse cellular and molecular environment to establish synaptic contacts with the …
traverse a diverse cellular and molecular environment to establish synaptic contacts with the …