Glycoconjugates: synthesis, functional studies, and therapeutic developments

SS Shivatare, VS Shivatare, CH Wong - Chemical reviews, 2022 - ACS Publications
Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …

Synthetic amorphous silica nanoparticles: toxicity, biomedical and environmental implications

JG Croissant, KS Butler, JI Zink, CJ Brinker - Nature Reviews Materials, 2020 - nature.com
Natural silica and silicates are predominantly crystalline and constitute the most abundant
components of the Earth's crust. Man-made silica is typically amorphous and manufactured …

Mesoporous silica nanoparticles for drug delivery

M Manzano, M Vallet‐Regí - Advanced functional materials, 2020 - Wiley Online Library
In recent years, nanomedicine has emerged at the forefront of nanotechnology, generating
great expectations in the biomedical field. Researchers are develo** novel nanoparticles …

Nanoarchitectured structure and surface biofunctionality of mesoporous silica nanoparticles

RK Kankala, YH Han, J Na, CH Lee, Z Sun… - Advanced …, 2020 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs), one of the important porous materials, have
garnered interest owing to their highly attractive physicochemical features and …

Nanoparticle-based drug delivery systems for cancer therapy

Y Dang, J Guan - Smart Materials in Medicine, 2020 - Elsevier
Nanoparticle-based drug delivery system (DDS) is considered promising for cancer
treatment. Compared with traditional DDS, the nanoparticle-based DDS shows improved …

Next‐generation vaccines: nanoparticle‐mediated DNA and mRNA delivery

W Ho, M Gao, F Li, Z Li, XQ Zhang… - Advanced healthcare …, 2021 - Wiley Online Library
Nucleic acid vaccines are a method of immunization aiming to elicit immune responses akin
to live attenuated vaccines. In this method, DNA or messenger RNA (mRNA) sequences are …

Chemically engineered mesoporous silica nanoparticles-based intelligent delivery systems for theranostic applications in multiple cancerous/non-cancerous diseases

S Zhou, Q Zhong, Y Wang, P Hu, W Zhong… - Coordination Chemistry …, 2022 - Elsevier
In recent years, the unprecedented advances of biomedical nanotechnology have spurred
the development of drug delivery systems (DDSs) based on multifarious nanomaterials in …

Tumor-selective catalytic nanomedicine by nanocatalyst delivery

M Huo, L Wang, Y Chen, J Shi - Nature communications, 2017 - nature.com
Tumor cells metabolize in distinct pathways compared with most normal tissue cells. The
resulting tumor microenvironment would provide characteristic physiochemical conditions …

Nanoparticle characterization: what to measure?

MM Modena, B Rühle, TP Burg, S Wuttke - Advanced Materials, 2019 - Wiley Online Library
What to measure? is a key question in nanoscience, and it is not straightforward to address
as different physicochemical properties define a nanoparticle sample. Most prominent …

The development of anticancer ruthenium (II) complexes: from single molecule compounds to nanomaterials

L Zeng, P Gupta, Y Chen, E Wang, L Ji… - Chemical Society …, 2017 - pubs.rsc.org
Cancer is rapidly becoming the top killer in the world. Most of the FDA approved anticancer
drugs are organic molecules, while metallodrugs are very scarce. The advent of the first …