Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission

G Livingston, J Huntley, KY Liu, SG Costafreda… - The Lancet, 2024 - thelancet.com
Executive summary The 2024 update of the Lancet Commission on dementia provides new
hopeful evidence about dementia prevention, intervention, and care. As people live longer …

Mitochondria: It is all about energy

A Casanova, A Wevers, S Navarro-Ledesma… - Frontiers in …, 2023 - frontiersin.org
Mitochondria play a key role in both health and disease. Their function is not limited to
energy production but serves multiple mechanisms varying from iron and calcium …

Social participation and risk of develo** dementia

A Sommerlad, M Kivimäki, EB Larson, S Röhr, K Shirai… - Nature aging, 2023 - nature.com
The increasing number of people with dementia globally illustrates the urgent need to
reduce dementia's scale and impact. Lifetime social participation may affect dementia risk by …

Association of adverse childhood experiences and social isolation with later-life cognitive function among adults in China

L Lin, B Cao, W Chen, J Li, Y Zhang… - JAMA network open, 2022 - jamanetwork.com
Importance Studies investigating the association of threat-related and deprivation-related
adverse childhood experiences (ACEs) with later-life cognitive decline are lacking …

[HTML][HTML] The impact of loneliness and social isolation on the development of cognitive decline and Alzheimer's disease

Y Ren, A Savadlou, S Park, P Siska, JR Epp… - Frontiers in …, 2023 - Elsevier
Alzheimer's Disease (AD) is the leading cause of dementia, observed at a higher incidence
in women compared with men. Treatments aimed at improving pathology in AD remain …

Links between COVID-19 and Parkinson's disease/Alzheimer's disease: reciprocal impacts, medical care strategies and underlying mechanisms

P Huang, LY Zhang, YY Tan, SD Chen - Translational Neurodegeneration, 2023 - Springer
The impact of coronavirus disease 2019 (COVID-19) pandemic on patients with
neurodegenerative diseases and the specific neurological manifestations of COVID-19 have …

[HTML][HTML] Associations between social health factors, cognitive activity and neurostructural markers for brain health–A systematic literature review and meta-analysis

LA Duffner, NR DeJong, JFA Jansen, WH Backes… - Ageing Research …, 2023 - Elsevier
Social health factors (eg, social activities or social support) and cognitive activity
engagement have been associated with dementia risk, but their neural substrates have not …

The relationship between social isolation, social support, and loneliness with cardiovascular disease and shared risk factors: A narrative review

AB Teshale, HL Htun, J Hu, LL Dalli, MH Lim… - Archives of gerontology …, 2023 - Elsevier
Background Cardiovascular disease (CVD) is the greatest contributor to global morbidity
and mortality. Poor social health plays a critical role in CVD incidence. Additionally, the …

[HTML][HTML] Lessons from lonely flies: Molecular and neuronal mechanisms underlying social isolation

RSP Yadav, F Ansari, N Bera, C Kent… - … & Biobehavioral Reviews, 2024 - Elsevier
Animals respond to changes in the environment which affect their internal state by adapting
their behaviors. Social isolation is a form of passive environmental stressor that alters …

Loneliness and risk of all-cause, Alzheimer's, vascular, and frontotemporal dementia: a prospective study of 492,322 individuals over 15 years

AR Sutin, M Luchetti, D Aschwanden, X Zhu… - International …, 2023 - cambridge.org
Objectives: This study examined the association between loneliness and risk of incident all-
cause dementia and whether the association extends to specific causes of dementia …