Dementia in Africa: Current evidence, knowledge gaps, and future directions

RO Akinyemi, J Yaria, A Ojagbemi… - Alzheimer's & …, 2022 - Wiley Online Library
In tandem with the ever‐increasing aging population in low and middle‐income countries,
the burden of dementia is rising on the African continent. Dementia prevalence varies from …

Epidemiology of neurodegenerative diseases in the East African region: A meta-analysis

H Onohuean, AO Akiyode, O Akiyode… - Frontiers in …, 2022 - frontiersin.org
Introduction There is a scarcity of epidemiological data on neurodegenerative diseases
(NDs) in East Africa. This meta-analysis provides the regional prevalence of NDs, their …

[HTML][HTML] Review of Alzheimer's disease drugs and their relationship with neuron-glia interaction

MK Ajenikoko, AO Ajagbe, OA Onigbinde… - IBRO Neuroscience …, 2023 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia worldwide. Because
Alzheimer's disease has no known treatment, sufferers and their caregivers must …

Burden of care and co** strategies among informal caregivers of people with behavioral and psychological symptoms of dementia in rural south-western Uganda

J Owokuhaisa, R Kamoga, P Musinguzi, M Muwanguzi… - BMC geriatrics, 2023 - Springer
Background Caregiving is a draining role that inflicts a significant level of burden upon
caregivers for older people with Behavioral and Psychological Symptoms of Dementia …

[HTML][HTML] Dementia screening in rural Kenya: The prevalence and impact of screening positive for dementia

CW Musyimi, DM Ndetei, LA Muyela, J Masila… - …, 2024 - karger.com
Abstract Introduction: In Kenya, there is a lack of data on the number of people with
dementia. In this article, we aim to estimate the number of community-dwelling older adults …

Neurons die with heightened but functional macro-and chaperone mediated autophagy upon increased amyloid-ß induced toxicity with region-specific protection in …

CM Ntsapi, B Loos - Experimental Cell Research, 2021 - Elsevier
Alzheimer's disease (AD) is a devastating neurodegenerative condition with significant socio-
economic impact that is exacerbated by the rapid increase in population aging, particularly …

Caring for people with dementia in rural Uganda: qualitative study of caregiving burden experienced by informal and formal caregivers

HE Ainamani, PE Alele, GZ Rukundo… - Journal of global …, 2020 - pmc.ncbi.nlm.nih.gov
Background The rising incidence of Alzheimer's disease among older-age adults worldwide
has been accompanied by an increase in caregiving burden. Limited work has examined …

Probing the multitargeting potential of n-hexane fraction of Gongronema latifolium leaves in neurodegeneration via in vitro, GC–MS and in silico studies

GA Gyebi, JC Ejoh, OM Ogunyemi, AM Ibrahim… - Future Journal of …, 2023 - Springer
Abstract Background Neurodegenerative disorders (NDDs) are associated with increased
activities of brain acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and …

Child maltreatment, cognitive functions and the mediating role of mental health problems among maltreated children and adolescents in Uganda

HE Ainamani, GZ Rukundo, T Nduhukire… - Child and adolescent …, 2021 - Springer
Background Child maltreatment poses high risks to the mental health and cognitive
functioning of children not only in childhood but also in later life. However, it remains unclear …

Prevalence of suspected dementia in a sample of adults living in Kinshasa‐Democratic Republic of the Congo

J Ikanga, A Reyes, D Kaba, P Akilimali… - Alzheimer's & …, 2023 - Wiley Online Library
Background The prevalence of dementia in Sub‐Saharan Africa, particularly in French‐
speaking countries, has received limited attention. This study investigates the prevalence …