The protein folding 'speed limit'
How fast can a protein possibly fold? This question has stimulated experimentalists to seek
fast folding proteins and to engineer them to fold even faster. Proteins folding at or near the …
fast folding proteins and to engineer them to fold even faster. Proteins folding at or near the …
Single-molecule fluorescence studies of protein folding and conformational dynamics
Single-molecule measurements provide unique information on heterogeneous populations
of molecules: They give access to the complete distribution of observables (rather than only …
of molecules: They give access to the complete distribution of observables (rather than only …
Optimized molecular dynamics force fields applied to the helix− coil transition of polypeptides
Obtaining the correct balance of secondary structure propensities is a central priority in
protein force-field development. Given that current force fields differ significantly in their α …
protein force-field development. Given that current force fields differ significantly in their α …
[HTML][HTML] Distinct α-synuclein strains differentially promote tau inclusions in neurons
Many neurodegenerative diseases are characterized by the accumulation of insoluble
protein aggregates, including neurofibrillary tangles comprised of tau in Alzheimer's disease …
protein aggregates, including neurofibrillary tangles comprised of tau in Alzheimer's disease …
[HTML][HTML] Exploring the helix-coil transition via all-atom equilibrium ensemble simulations
EJ Sorin, VS Pande - Biophysical journal, 2005 - cell.com
The ensemble folding of two 21-residue α-helical peptides has been studied using all-atom
simulations under several variants of the AMBER potential in explicit solvent using a global …
simulations under several variants of the AMBER potential in explicit solvent using a global …
Rapid detection and quantification of milk adulteration using infrared microspectroscopy and chemometrics analysis
The application of attenuated total reflectance mid-infrared microspectroscopy (MIR-
microspectroscopy) was evaluated as a rapid method for detection and quantification of milk …
microspectroscopy) was evaluated as a rapid method for detection and quantification of milk …
Infrared probes for studying the structure and dynamics of biomolecules
The first step toward understanding most of the chemical and biological processes in
condensed phases is to accurately describe solute− solvent interaction energy and to …
condensed phases is to accurately describe solute− solvent interaction energy and to …
Combined electronic structure/molecular dynamics approach for ultrafast infrared spectroscopy of dilute HOD in liquid H2O and D2O
We present a new approach that combines electronic structure methods and molecular
dynamics simulations to investigate the infrared spectroscopy of condensed phase systems …
dynamics simulations to investigate the infrared spectroscopy of condensed phase systems …
Using nitrile-derivatized amino acids as infrared probes of local environment
Z Getahun, CY Huang, T Wang… - Journal of the …, 2003 - ACS Publications
It is well-known that the C⋮ N stretching vibration in acetonitrile is sensitive to solvent.
Therefore, we proposed in this contribution to use this vibrational mode to report local …
Therefore, we proposed in this contribution to use this vibrational mode to report local …
Site-specific infrared probes of proteins
Infrared spectroscopy has played an instrumental role in the study of a wide variety of
biological questions. However, in many cases, it is impossible or difficult to rely on the …
biological questions. However, in many cases, it is impossible or difficult to rely on the …