The X chromosome and X-linked variants have largely been ignored in genome-wide and
candidate association studies of infectious diseases due to the complexity of statistical …

Neurological and neuropsychiatric disorders affect men and women differently. Multiple
sclerosis, Alzheimer's disease, anxiety disorders, depression, meningiomas and late-onset …

A hallmark of chromosome organization is the partition into transcriptionally active A and
repressed B compartments, and into topologically associating domains (TADs). Both …

Long non-coding RNAs (lncRNAs) are largely involved in the development of osteoarthritis
(OA), a chronic and degenerative joint disease. The objective of this paper is to research the …

X-chromosome inactivation (XCI) is a process involved in the pathogenesis of several
diseases. In this mini review, we discuss the known mechanisms associated with XCI, when …

Simple Summary Horse chromosomes have been studied for veterinary diagnostic purposes
for over half a century. The findings show that changes in the chromosome number or …

Induction and reversal of chromatin silencing is critical for successful development, tissue
homeostasis, and the derivation of induced pluripotent stem cells (iPSCs). X-Chromosome …

Human induced Pluripotent Stem Cells (hiPSCs) have the capacity to generate a wide range
of somatic cells, thus representing an ideal tool for regenerative medicine. Patient-derived …