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Green synthesis of biologically active heterocycles of medicinal importance: A review
Heterocyclic moieties are basic skeletons for 80% of commercial medicines according to the
US retail market in 2014–2015, yet many actual synthetic methods are not sustainable …
US retail market in 2014–2015, yet many actual synthetic methods are not sustainable …
Recent Advances in the Synthesis of Imidazo[1,2‐a]pyridines: A Brief Review
This review focuses on providing comprehensive highlights of the recent synthetic pathways
of imidazo [1, 2‐a] pyridines, assisted through transition metal‐catalyzed reactions, multi …
of imidazo [1, 2‐a] pyridines, assisted through transition metal‐catalyzed reactions, multi …
A concise review of multicomponent reactions using novel heterogeneous catalysts under microwave irradiation
Multi-component reactions for the construction of heterocycles have been fascinated by
microwave energy as an alternative technique of heating, owing to the advantages over …
microwave energy as an alternative technique of heating, owing to the advantages over …
2-Aminopyridine–an unsung hero in drug discovery
RN Rao, K Chanda - Chemical Communications, 2022 - pubs.rsc.org
2-Aminopyridine is a simple, low molecular weight and perfectly functionalised moiety
known for the synthesis of diverse biological molecules. Many pharmaceutical companies …
known for the synthesis of diverse biological molecules. Many pharmaceutical companies …
Trihaloisocyanuric acids in ethanol: an eco-friendly system for the regioselective halogenation of imidazo-heteroarenes
JSS Neto, RA Balaguez, MS Franco… - Green …, 2020 - pubs.rsc.org
Herein, we describe an efficient, rapid and benign protocol for the direct C (sp2)–H bond
halogenation (Cl, Br, I) of 2-arylimidazo [1, 2-a] pyridines using trihaloisocyanuric acids in …
halogenation (Cl, Br, I) of 2-arylimidazo [1, 2-a] pyridines using trihaloisocyanuric acids in …
Sequencing [3+ 2]-cycloaddition and multicomponent reactions: A regioselective microwave-assisted synthesis of 1, 4-disubstituted 1, 2, 3-triazoles using ionic liquid …
Heterocyclic compounds with two to three nitrogen atoms play a pivotal role in the normal
life cycle of a cell. Further the design and synthesis of a quality heterocyclic compound …
life cycle of a cell. Further the design and synthesis of a quality heterocyclic compound …
The application of microwaves, ultrasounds, and their combination in the synthesis of nitrogen-containing bicyclic heterocycles
F Frecentese, F Sodano, A Corvino… - International journal of …, 2023 - mdpi.com
The use of alternative energy sources, such as microwaves (MW) or ultrasounds (US), and
their mutual cross-combination have been widely described in the literature in the …
their mutual cross-combination have been widely described in the literature in the …
Microwave‐assisted synthesis and luminescent activity of imidazo[1,2‐a]pyridine derivatives
JC Rodríguez, RA Maldonado… - Journal of …, 2020 - Wiley Online Library
In this work, a series of phenacyl bromide derivatives was synthesized and employed as key
intermediate for the synthesis of substituted imidazo [1, 2‐a] pyridines. First, phenacyl …
intermediate for the synthesis of substituted imidazo [1, 2‐a] pyridines. First, phenacyl …
Visible-Light-Initiated One-Pot, Three-Component Synthesis of 2-Amino-4H-pyran-3,5-dicarbonitrile Derivatives
M Zhang, MN Chen, JM Li, N Liu… - ACS Combinatorial …, 2019 - ACS Publications
A novel approach for the visible-light-initiated synthesis of 2-amino-4 H-pyran-3, 5-
dicarbonitrile derivatives via a one-pot, three-component reaction of aldehydes or isatins …
dicarbonitrile derivatives via a one-pot, three-component reaction of aldehydes or isatins …
Pyrimidine-fused dinitrogenous penta-heterocycles as a privileged scaffold for anti-cancer drug discovery
W Li, J Zhang, M Wang, R Dong, X Zhou… - Current Topics in …, 2022 - benthamdirect.com
Pyrimidine-fused derivatives that are the inextricable part of DNA and RNA play a key role in
the normal life cycle of cells. Pyrimidine-fused dinitrogenous penta-heterocycles, including …
the normal life cycle of cells. Pyrimidine-fused dinitrogenous penta-heterocycles, including …