Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential

M Yuan, B Yang, G Rothschild, JJ Mann… - Signal transduction and …, 2023 - nature.com
Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …

[HTML][HTML] Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders

MMJ Van den Berg, J Krauskopf, JG Ramaekers… - Progress in …, 2020 - Elsevier
Circulating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …

MicroRNA profiling: approaches and considerations

CC Pritchard, HH Cheng, M Tewari - Nature Reviews Genetics, 2012 - nature.com
MicroRNAs (miRNAs) are small RNAs that post-transcriptionally regulate the expression of
thousands of genes in a broad range of organisms in both normal physiological contexts …

Circulating microRNAs: Biomarkers of disease

Y Wu, Q Li, R Zhang, X Dai, W Chen, D **ng - Clinica Chimica Acta, 2021 - Elsevier
MicroRNAs are a class of endogenous noncoding single-stranded RNA molecules with
approximately 20–24 nucleotides and are associated with a broad range of biological …

microRNAs in Parkinson's disease: from pathogenesis to novel diagnostic and therapeutic approaches

L Leggio, S Vivarelli, F L'Episcopo, C Tirolo… - International journal of …, 2017 - mdpi.com
Parkinson's disease (PD) is the most prevalent central nervous system (CNS) movement
disorder and the second most common neurodegenerative disease overall. PD is …

Epigenetic mechanisms in schizophrenia and other psychotic disorders: a systematic review of empirical human findings

L Smigielski, V Jagannath, W Rössler, S Walitza… - Molecular …, 2020 - nature.com
Schizophrenia and other psychotic disorders are highly debilitating psychiatric conditions
that lack a clear etiology and exhibit polygenic inheritance underlain by pleiotropic genes …

Epigenetic modifications in schizophrenia and related disorders: molecular scars of environmental exposures and source of phenotypic variability

J Richetto, U Meyer - Biological Psychiatry, 2021 - Elsevier
Epigenetic modifications are increasingly recognized to play a role in the etiology and
pathophysiology of schizophrenia and other psychiatric disorders with developmental …

Circulating miRNA biomarkers for Alzheimer's disease

P Kumar, Z Dezso, C MacKenzie, J Oestreicher… - PloS one, 2013 - journals.plos.org
A minimally invasive diagnostic assay for early detection of Alzheimer's disease (AD) is
required to select optimal patient groups in clinical trials, monitor disease progression and …

MicroRNA schizophrenia: etiology, biomarkers and therapeutic targets

HC Zhang, Y Du, L Chen, ZQ Yuan, Y Cheng - … & Biobehavioral Reviews, 2023 - Elsevier
The three sets of symptoms associated with schizophrenia—positive, negative, and
cognitive—are burdensome and have serious effects on public health, which affects up to …

MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function

BH Miller, Z Zeier, L **, TA Lanz, S Deng… - Proceedings of the …, 2012 - pnas.org
Schizophrenia is characterized by affective, cognitive, neuromorphological, and molecular
abnormalities that may have a neurodevelopmental origin. MicroRNAs (miRNAs) are small …