The role of oxidative stress in hyperuricemia and xanthine oxidoreductase (XOR) inhibitors

N Liu, H Xu, Q Sun, X Yu, W Chen… - Oxidative Medicine …, 2021 - Wiley Online Library
Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …

[HTML][HTML] Hyperuricemia-related diseases and xanthine oxidoreductase (XOR) inhibitors: an overview

C Chen, JM Lü, Q Yao - Medical science monitor: international …, 2016 - ncbi.nlm.nih.gov
Uric acid is the final oxidation product of purine metabolism in humans. Xanthine
oxidoreductase (XOR) catalyzes oxidative hydroxylation of hypoxanthine to xanthine to uric …

Oxidative stress, extracellular matrix targets, and idiopathic pulmonary fibrosis

CR Kliment, TD Oury - Free Radical Biology and Medicine, 2010 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by
progressive fibrosis of the alveolar interstitium. The pathogenesis is thought to involve …

Linking exposure to environmental pollutants with biological effects

M Sørensen, H Autrup, P Møller, O Hertel… - … Research/Reviews in …, 2003 - Elsevier
Exposure to ambient air pollution has been associated with cancer. Ambient air contains a
complex mixture of toxics, including particulate matter (PM) and benzene. Carcinogenic …

Roles of oxidative stress in signaling and inflammation induced by particulate matter

F Mazzoli-Rocha, S Fernandes… - Cell biology and …, 2010 - Springer
This review reports the role of oxidative stress in impairing the function of lung exposed to
particulate matter (PM). PM constitutes a heterogeneous mixture of various types of particles …

Low plasma uric acid level in Parkinson's disease

T Annanmaki, A Muuronen, K Murros - Movement disorders, 2007 - Wiley Online Library
Earlier studies suggest that low plasma uric acid level is a risk factor for Parkinson's disease
(PD), and that uric acid associates with iron‐binding proteins. We therefore decided to …

[HTML][HTML] Hemin and iron increase synthesis and trigger export of xanthine oxidoreductase from hepatocytes to the circulation

ER DeVallance, HM Schmidt, M Seman, SE Lewis… - Redox Biology, 2023 - Elsevier
We recently reported a previously unknown salutary role for xanthine oxidoreductase (XOR)
in intravascular heme overload whereby hepatocellular export of XOR to the circulation was …

Thermocatalytic conversion of lignin in an ethanol/formic acid medium with NiMo catalysts: Role of the metal and acid sites

M Oregui-Bengoechea, I Gandarias, N Miletić… - Applied Catalysis B …, 2017 - Elsevier
NiMo catalysts supported on different sulfated and non-sulfated aluminas and zirconias
were studied for the catalytic conversion of lignin in a formic acid/ethanol medium. All the pre …

Shared perturbations in the metallome and metabolome of Alzheimer's, Parkinson's, Huntington's, and dementia with Lewy bodies: A systematic review

M Scholefield, RD Unwin, GJS Cooper - Ageing research reviews, 2020 - Elsevier
Despite differences in presentation, age-related dementing diseases such as Alzheimer's
(AD), Parkinson's (PD), and Huntington's diseases (HD), and dementia with Lewy bodies …

The relationship between ferritin and urate levels and risk of gout

T Fatima, C McKinney, TJ Major, LK Stamp… - Arthritis research & …, 2018 - Springer
Background Ferritin positively associates with serum urate and an interventional study
suggests that iron has a role in triggering gout flares. The objective of this study was to …