Functions and biosynthesis of plasmalogens in health and disease

P Brites, HR Waterham, RJA Wanders - … BBA)-Molecular and Cell Biology of …, 2004 - Elsevier
Plasmalogens (1-O-alk-1′-enyl-2-acyl glycerophospholipids) constitute a special class of
phospholipids characterized by the presence of a vinyl–ether bond at the sn-1 position …

Nervonic acid and its sphingolipids: Biological functions and potential food applications

NV Phung, F Rong, WY **a, Y Fan, XY Li… - Critical reviews in …, 2024 - Taylor & Francis
Nervonic acid, a 24-carbon fatty acid with only one double bond at the 9th carbon (C24: 1n-
9), is abundant in the human brain, liver, and kidney. It not only functions in free form but …

The biochemistry of peroxisomal β-oxidation in the yeast Saccharomyces cerevisiae

JK Hiltunen, AM Mursula… - FEMS microbiology …, 2003 - academic.oup.com
Peroxisomal fatty acid degradation in the yeast Saccharomyces cerevisiae requires an array
of β-oxidation enzyme activities as well as a set of auxiliary activities to provide the β …

The Arabidopsis pxa1 Mutant Is Defective in an ATP-Binding Cassette Transporter-Like Protein Required for Peroxisomal Fatty Acid β-Oxidation

BK Zolman, ID Silva, B Bartel - Plant Physiology, 2001 - academic.oup.com
Peroxisomes are important organelles in plant metabolism, containing all the enzymes
required for fatty acid β-oxidation. More than 20 proteins are required for peroxisomal …

Impaired very long-chain acyl-CoA β-oxidation in human X-linked adrenoleukodystrophy fibroblasts is a direct consequence of ABCD1 transporter dysfunction

C Wiesinger, M Kunze, S Forss-Petter… - Journal of Biological …, 2013 - ASBMB
X-linked adrenoleukodystrophy (X-ALD), an inherited peroxisomal disorder, is caused by
mutations in the ABCD1 gene encoding the peroxisomal ATP-binding cassette (ABC) …

[HTML][HTML] Peroxisomal acyl-CoA synthetases

PA Watkins, JM Ellis - Biochimica et Biophysica Acta (BBA)-molecular basis …, 2012 - Elsevier
Peroxisomes carry out many essential lipid metabolic functions. Nearly all of these functions
require that an acyl group—either a fatty acid or the acyl side chain of a steroid derivative …

The biochemistry and physiology of long-chain dicarboxylic acid metabolism

P Ranea-Robles, SM Houten - Biochemical Journal, 2023 - portlandpress.com
Mitochondrial β-oxidation is the most prominent pathway for fatty acid oxidation but
alternative oxidative metabolism exists. Fatty acid ω-oxidation is one of these pathways and …

General aspects and neuropathology of X‐linked adrenoleukodystrophy

I Ferrer, P Aubourg, A Pujol - Brain pathology, 2010 - Wiley Online Library
Abstract X‐adrenoleukodystrophy (X‐ALD) is a metabolic, peroxisomal disease affecting the
nervous system, adrenal cortex and testis resulting from inactivating mutations in ABCD1 …

Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling

SJ Mihalik, SJ Steinberg, Z Pei, J Park, DG Kim… - Journal of Biological …, 2002 - ASBMB
Bile acids are synthesized de novo in the liver from cholesterol and conjugated to glycine or
taurine via a complex series of reactions involving multiple organelles. Bile acids secreted …

[HTML][HTML] Peroxisomal ABC transporters

FL Theodoulou, M Holdsworth, A Baker - FEBS letters, 2006 - Elsevier
Peroxisomes perform a range of different functions, dependent upon organism, tissue type,
developmental stage or environmental conditions, many of which are connected with lipid …