Cardiovascular diseases (CVDs) constitute the prime cause of global mortality, with an
immense impact on patient quality of life and disability. Clinical evidence has revealed a …

Prostate cancer belongs in the class of hormone-dependent cancers, representing a major
cause of cancer incidence in men worldwide. Since upon disease onset almost all prostate …

Cellular senescence constitutes a generally irreversible proliferation barrier, accompanied
by macromolecular damage and metabolic rewiring. Several senescence types have been …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by the
accumulation of amyloid-β (Aβ) in the brain. The gut/brain axis may serve a role in AD …

Background Prostate cancer is a major cause of cancer morbidity and mortality in men
worldwide. Androgen deprivation therapy (ADT) has proven effective in early-stage …

Aim: The mechanism of RASSF1A in DNA damage repair remains to be further clarified for
applying to synthetic lethal strategy. Materials & methods: Eight esophageal cancer cell …

Gastroenteropancreatic neuroendocrine neoplasms are a rare, diverse group of
neuroendocrine tumors that form in the pancreatic and gastrointestinal tract, and often …

In cancer, synthetic lethality refers to the drug-induced inactivation of one gene and the
inhibition of another in cancer cells by a drug, resulting in the death of only cancer cells; …

目的: 探究丝氨酸精子发生相关蛋白2 (spermatogenesis associated serine rich 2, SPATS2)
影响喉鳞状细胞癌(larynx squamous cell carcinoma, LSCC) 增殖, 迁移, 侵袭和上皮间质转化 …