Listeriosis is a serious food-borne illness, especially in susceptible populations, including
children, pregnant women, and elderlies. The disease can occur in two forms: non-invasive …

Listeria monocytogenes is well recognized for both its broad resistance to stress conditions
and its ability to transition from a soil bacterium to an intracellular pathogen of mammalian …

Pathogenic bacteria rely on secreted virulence factors to cause disease in susceptible hosts.
However, in Gram-positive bacteria, the mechanisms underlying secreted protein activation …

The tight and coordinated regulation of virulence gene expression is crucial to ensure the
survival and persistence of bacterial pathogens in different contexts within their hosts …

Bacterial lipoproteins are secreted membrane‐anchored proteins characterized by a lipobox
motif. This lipobox motif directs post‐translational modifications at the conserved cysteine …

Background PrsA is an extracytoplasmic folding catalyst essential in Bacillus subtilis.
Overexpression of the native PrsA from B. subtilis has repeatedly lead to increased amylase …

Bacterial pathogens often employ RNA regulatory elements located in the 5′ untranslated
regions (UTRs) to control gene expression. Using a comparative structural analysis, we …

Background Staphylococcus aureus secretes a variety of proteins including virulence factors
that cause diseases. PrsA, encoded by many Gram-positive bacteria, is a membrane …

Listeria monocytogenes (Lm) is a widespread environmental Gram‐positive bacterium that
can transition into a pathogen following ingestion by a susceptible host. To cross host …

Horizontal gene transfer is an important means of bacterial evolution. This includes natural
genetic transformation, where bacterial cells become “competent” and DNA is acquired from …