Effects of super-class cannabis terpenes beta-caryophyllene and alpha-pinene on zebrafish behavioural biomarkers

A Johnson, A Stewart, I El-Hakim, TJ Hamilton - Scientific Reports, 2022 - nature.com
Terpenes possess a wide range of medicinal properties and are potential therapeutics for a
variety of pathological conditions. This study investigated the acute effects of two cannabis …

[HTML][HTML] Cannabinoid type-2 receptors modulate terpene induced anxiety-reduction in zebrafish

AL Johnson, R Verbitsky, J Hudson, R Dean… - Biomedicine & …, 2023 - Elsevier
Terpenes are the most extensive and varied group of naturally occurring compounds mostly
found in plants, including cannabis, and have an array of potential therapeutic benefits for …

β-Carboline (FG-7142) modulates fear but not anxiety-like behaviour in zebrafish

KR Scatterty, TJ Hamilton - Scientific Reports, 2024 - nature.com
The β-Carboline FG-7142 is a partial inverse agonist at the benzodiazepine allosteric site on
the GABA-A receptor that induces anxiogenic, proconvulsant, and appetite-reducing effects …

Robust behavioural effects in response to acute, but not repeated, terpene administration in Zebrafish (Danio rerio)

J Szaszkiewicz, S Leigh, TJ Hamilton - Scientific reports, 2021 - nature.com
Terpenes are fragrant aromatic compounds produced by a variety of plants, most notably
cannabis and hops. With increasing legalization of cannabis there is a need to better …

Sex, drugs, and zebrafish: Acute exposure to anxiety-modulating compounds in a modified novel tank dive test

AL Johnson, PL Hurd, TJ Hamilton - Pharmacology Biochemistry and …, 2024 - Elsevier
This study investigated the effects of anxiogenic and anxiolytic drugs on zebrafish (Danio
rerio) behaviour using a modified novel tank dive test with higher walls and a narrower …

Wall-following behavior: Its ultimate and proximate explanations, prevalence, and implications

I Scharf, A Farji-Brener - Advances in Applied Microbiology, 2024 - cris.bgu.ac.il
Wall-following behavior is the movement along a wall exhibited by various animals. It is a
conserved behavior among taxa, from unicellular organisms to humans, prone to selection …

The dose makes the poison: Non-linear behavioural response to CO2-induced aquatic acidification in zebrafish (Danio rerio)

TJ Hamilton, NH Radke, J Bajwa, S Chaput… - Science of The Total …, 2021 - Elsevier
CO 2-induced aquatic acidification is predicted to affect fish neuronal GABA A receptors
leading to widespread behavioural alterations. However, the large variability in the …

[HTML][HTML] Analysis of the potential behavioral impact of methanol when used as a solvent: Dataset from zebrafish (Danio rerio) behavioral research

TJ Hamilton, J Szaszkiewicz, J Krook, W Burggren - Data in Brief, 2021 - Elsevier
Toxicants are commonly administered to experimental organisms using solvents as
vehicles. One common vehicle for dissolving toxicants is methanol (CH 3 OH), a solvent …