Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose
Understanding the impact of age on vaccinations is essential for the design and delivery of
vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of …
vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of …
Immunological Studies to Understand Hybrid/Recombinant Variants of SARS-CoV-2
The zoonotic SARS-CoV-2 virus was present before the onset of the pandemic. It undergoes
evolution, adaptation, and selection to develop variants that gain high transmission rates …
evolution, adaptation, and selection to develop variants that gain high transmission rates …
Decreased memory B cell frequencies in COVID‐19 delta variant vaccine breakthrough infection
Abstract The SARS‐CoV‐2 Delta (B. 1.617. 2) variant is capable of infecting vaccinated
persons. An open question remains as to whether deficiencies in specific vaccine‐elicited …
persons. An open question remains as to whether deficiencies in specific vaccine‐elicited …
Waning of specific antibodies against Delta and Omicron variants five months after a third dose of BNT162b2 SARS-CoV-2 vaccine in elderly individuals
The emergence of new SARS-CoV-2 variants, such as the more transmissible Delta and
Omicron variants, has raised concerns on efficacy of the COVID-19 vaccines. Here, we …
Omicron variants, has raised concerns on efficacy of the COVID-19 vaccines. Here, we …
Engineering immunosuppressive drug-resistant armored (IDRA) SARS-CoV-2 T cells for cell therapy
Q Chen, A Chia, SK Hang, A Lim, WK Koh… - Cellular & molecular …, 2023 - nature.com
Solid organ transplant (SOT) recipients receive immunosuppressive drugs (ISDs) and are
susceptible to develo** severe COVID-19. Here, we analyze the Spike-specific T-cell …
susceptible to develo** severe COVID-19. Here, we analyze the Spike-specific T-cell …
Prolonged inflammation in patients hospitalized for coronavirus disease 2019 (COVID‐19) resolves 2 years after infection
Long‐term complications from coronavirus disease 2019 (COVID‐19) are concerning, as
survivors can develop subclinical multiorgan dysfunction. It is unknown if such complications …
survivors can develop subclinical multiorgan dysfunction. It is unknown if such complications …
Heterologous booster vaccination with CoronaVac following prime vaccination with mRNA vaccine
Objective Despite the high vaccine efficacy of mRNA COVID‐19 vaccines, there are
individuals who developed excessive reactogenic and/or allergic responses after the first …
individuals who developed excessive reactogenic and/or allergic responses after the first …
Variant-Specific IgA Protects Against Omicron Infection
Background The emergence of rapidly evolving severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) variants, coupled with waning vaccine-induced immunity, has …
coronavirus 2 (SARS-CoV-2) variants, coupled with waning vaccine-induced immunity, has …
Higher Delta variant-specific neutralizing antibodies prevented infection in close contacts vaccinated with ancestral mRNA vaccines during the SARS-CoV-2 Delta …
Identification of the risk factors and the high-risk groups which are most vulnerable is critical
in COVID-19 disease management at a population level. Evaluating the efficacy of …
in COVID-19 disease management at a population level. Evaluating the efficacy of …
First SARS-CoV-2 Omicron infection as an effective immune booster among mRNA vaccinated individuals: final results from the first phase of the PRIBIVAC …
Summary Background Understanding how SARS-CoV-2 breakthrough infections impacts
the breadth of immune responses against existing and pre-emergent SARS-CoV-2 strains is …
the breadth of immune responses against existing and pre-emergent SARS-CoV-2 strains is …