Background The time course of blood lactate levels could be helpful to assess a patient's
response to therapy. Although the focus of published studies has been largely on septic …

Lactate levels are commonly evaluated in acutely ill patients. Although most often used in
the context of evaluating shock, lactate levels can be elevated for many reasons. While …

Introduction There is no consensus definition of acute renal failure (ARF) in critically ill
patients. More than 30 different definitions have been used in the literature, creating much …

Objective: To determine the prevalence and impact on mortality of delays in initiation of
effective antimicrobial therapy from initial onset of recurrent/persistent hypotension of septic …

Rationale: It is unknown whether lactate monitoring aimed to decrease levels during initial
treatment in critically ill patients improves outcome. Objectives: To assess the effect of lactate …

Mitochondrial structures were probably observed microscopically in the 1840s, but the idea
of oxidative phosphorylation (OXPHOS) within mitochondria did not appear until the 1930s …

Background Using blood lactate monitoring for risk assessment in the critically ill patient
remains controversial. Some of the discrepancy is due to uncertainty regarding the …

Service organizations face a trade-off between high utilization and responsiveness. High
utilization can improve financial performance, but causes congestion, which increases …

Background: Currently, specific triage criteria, such as blood pressure, respiratory status,
Glasgow Coma Scale, and mechanism of injury are used to categorize trauma patients and …

Introduction When the number of patients who require intensive care is greater than the
number of beds available, intensive care unit (ICU) entry flow is obstructed. This …