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Visible-to-NIR-light activated release: from small molecules to nanomaterials
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
Development of organic semiconducting materials for deep-tissue optical imaging, phototherapy and photoactivation
Biophotonics as a highly interdisciplinary frontier often requires the assistance of optical
agents to control the light pathways in cells, tissues and living organisms for specific …
agents to control the light pathways in cells, tissues and living organisms for specific …
Polymer–drug conjugate therapeutics: advances, insights and prospects
Polymer–drug conjugates have long been a mainstay of the drug delivery field, with several
conjugates successfully translated into clinical practice. The conjugation of therapeutic …
conjugates successfully translated into clinical practice. The conjugation of therapeutic …
Photosensitizers with aggregation‐induced emission: Materials and biomedical applications
Photodynamic therapy is arising as a noninvasive treatment modality for cancer and other
diseases. One of the key factors to determine the therapeutic function is the efficiency of …
diseases. One of the key factors to determine the therapeutic function is the efficiency of …
Nanotechnology for multimodal synergistic cancer therapy
The complexity, diversity, and heterogeneity of tumors seriously undermine the therapeutic
potential of treatment. Therefore, the current trend in clinical research has gradually shifted …
potential of treatment. Therefore, the current trend in clinical research has gradually shifted …
Current status and prospects of MOFs in controlled delivery of Pt anticancer drugs
J Chen, Z Zhang, J Ma, A Nezamzadeh-Ejhieh… - Dalton …, 2023 - pubs.rsc.org
Cancer has become the second leading reason for death in the world. Still, cancer therapy
development is exceptionally challenging because the tumor microenvironment is very …
development is exceptionally challenging because the tumor microenvironment is very …
Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapy
W Zhang, X Hu, Q Shen, D **ng - Nature communications, 2019 - nature.com
Cancer cells exhibit slightly elevated levels of reactive oxygen species (ROS) compared with
normal cells, and approximately 90% of intracellular ROS is produced in mitochondria. In …
normal cells, and approximately 90% of intracellular ROS is produced in mitochondria. In …
Stepwise targeted strategies for improving neurological function by inhibiting oxidative stress levels and inflammation following ischemic stroke
Y Li, J Liao, L **ong, Z **ao, F Ye, Y Wang… - Journal of Controlled …, 2024 - Elsevier
Ischemia-reperfusion injury is caused by excessive production of reactive oxygen species
(ROS) and inflammation accompanied by ischemic injury symptoms and blood–brain barrier …
(ROS) and inflammation accompanied by ischemic injury symptoms and blood–brain barrier …
ROS-responsive nano-drug delivery system combining mitochondria-targeting ceria nanoparticles with atorvastatin for acute kidney injury
H Yu, F **, D Liu, G Shu, X Wang, J Qi, M Sun… - …, 2020 - pmc.ncbi.nlm.nih.gov
Acute kidney injury (AKI) caused by sepsis is a serious disease which mitochondrial
oxidative stress and inflammatory play a key role in its pathophysiology. Ceria nanoparticles …
oxidative stress and inflammatory play a key role in its pathophysiology. Ceria nanoparticles …
Role of reactive oxygen species (ROS) in therapeutics and drug resistance in cancer and bacteria
AT Dharmaraja - Journal of medicinal chemistry, 2017 - ACS Publications
Evading persistent drug resistance in cancer and bacteria is quintessential to restore health
in humans, and impels intervention strategies. A distinct property of the cancer phenotype is …
in humans, and impels intervention strategies. A distinct property of the cancer phenotype is …