Whole genome sequencing (WGS) promises to be transformative for the practice of clinical
microbiology, and the rapidly falling cost and turnaround time mean that this will become a …

Climate change has emerged as a major pressing global issue with far-reaching
implications for human health, such as the emerging and spread of food-borne pathogens …

Whole genome sequencing (WGS) shows great potential for real-time monitoring and
identification of infectious disease outbreaks. However, rapid and reliable comparison of …

The seventh cholera pandemic has heavily affected Africa, although the origin and
continental spread of the disease remain undefined. We used genomic data from 1070 …

Accurate strain identification is essential for anyone working with bacteria. For many
species, multilocus sequence ty** (MLST) is considered the “gold standard” of ty**, but …

Whole-genome sequencing (WGS) is becoming available as a routine tool for clinical
microbiology. If applied directly on clinical samples, this could further reduce diagnostic …

Ty** of methicillin-resistant Staphylococcus aureus (MRSA) is important in infection
control and surveillance. The current nomenclature of MRSA includes the genetic …

Objectives Antimicrobial susceptibility testing of bacterial isolates is essential for clinical
diagnosis, to detect emerging problems and to guide empirical treatment. Current …

Innovations in sequencing technologies have allowed biologists to make incredible
advances in understanding biological systems. As experience grows, researchers …

Background Accurately identifying single-nucleotide polymorphisms (SNPs) from bacterial
sequencing data is an essential requirement for using genomics to track transmission and …