[HTML][HTML] Converging Pathways between Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) and Diabetes in Children

MF Faienza, I Farella, M Khalil… - International Journal of …, 2024 - mdpi.com
In the past thirty years, childhood obesity rates have risen significantly worldwide, affecting
over 340 million children in affluent nations. This surge is intricately tied to metabolic …

[HTML][HTML] The biological clock of liver metabolism in metabolic dysfunction-associated steatohepatitis progression to hepatocellular carcinoma

PK Rajan, UAS Udoh, R Finley, SV Pierre, J Sanabria - Biomedicines, 2024 - mdpi.com
Circadian rhythms are endogenous behavioral or physiological cycles that are driven by a
daily biological clock that persists in the absence of geophysical or environmental temporal …

[HTML][HTML] Ramadan Fasting in Individuals with Metabolic Dysfunction-Associated Steatotic Liver Disease, Liver Transplant, and Bariatric Surgery: A Narrative Review

M Ahmed, MH Ahmed - Journal of Clinical Medicine, 2024 - mdpi.com
Metabolic dysfunction-associated steatotic liver disease is a growing worldwide pandemic. A
limited number of studies have investigated the potential effect of Ramadan fasting on …

[HTML][HTML] Nicotinamide Adenine Dinucleotide Phosphate Oxidases and Metabolic Dysfunction-Associated Steatotic Liver Disease

V Cammisotto, E Valeriani, P Pignatelli, F Violi - Antioxidants, 2025 - mdpi.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by lipid
accumulation in the liver due to an excess in their supplies or an impairment in their …

Adipose triglyceride lipase as a target for treatment of metabolic dysfunction-associated steatohepatitis: the role of hepatic and intestinal PPARα

FJ Gonzalez, Y **a - Journal of Hepatology, 2024 - journal-of-hepatology.eu
Adipose triglyceride lipase (ATGL), encoded by the PNPLA2 gene in humans, hydrolyzes
triacylglycerols to diacylglycerols. PNPLA2 is regulated by insulin, and under conditions of …

Effect of Fatty Acids on Glucose Metabolism and Type 2 Diabetes

D Sivri, Y Akdevelioğlu - Nutrition Reviews, 2024 - academic.oup.com
Type 2 diabetes is an inflammatory, non-infectious disease characterized by dysfunctional
pancreatic β-cells and insulin resistance. Although lifestyle, genetic, and environmental …

[HTML][HTML] Curcumin Mitigates Gut Dysbiosis and Enhances Gut Barrier Function to Alleviate Metabolic Dysfunction in Obese, Aged Mice

G Lamichhane, F Olawale, J Liu, DY Lee, SJ Lee… - Biology, 2024 - mdpi.com
The gut microbiome plays a critical role in maintaining gut and metabolic health, and its
composition is often altered by aging and obesity. This study aimed to investigate the …

Serum uric acid and nonalcoholic fatty liver disease

J Fan, D Wang - Frontiers in Endocrinology, 2024 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) is characterized by over 5% hepatic fat
accumulation without secondary causes. The prevalence of NAFLD has escalated in recent …

[HTML][HTML] Lethal Arrhythmogenic Role of Left Ventricular Myocardial Interstitial Fibrosis in Apolipoprotein E/Low-Density Lipoprotein Receptor Double-Knockout Mice …

J Liu, Y Oba, Y Kondo, R Nakaki… - International Journal of …, 2024 - mdpi.com
The combination of alcohol and a low-carbohydrate, high-protein, high-fat atherogenic diet
(AD) increases the risk of lethal arrhythmias in apolipoprotein E/low-density lipoprotein …

Correlation between hepatic steatosis severity diagnosed by ultrasound and metabolic indexes in elderly patients with MAFLD

Z Liang, R Huang, L Zhang - Frontiers in Medicine, 2025 - frontiersin.org
Objective To explore the connection between metabolic parameters and the severity of
hepatic steatosis determined through ultrasound in elderly individuals with metabolic …