Recent advances and prospects in nanomaterials for bacterial sepsis management

C Zhou, Y Liu, Y Li, L Shi - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Bacterial sepsis is a life-threatening condition caused by bacteria entering the bloodstream
and triggering an immune response, underscoring the importance of early recognition and …

Nitric oxide‐assisted photodynamic therapy for enhanced penetration and hypoxic bacterial biofilm elimination

X Lv, J Jiang, J Ren, H Li, D Yang… - Advanced …, 2023 - Wiley Online Library
The presence of a biofilm matrix barrier and hypoxic microenvironment within the biofilm
significantly impedes the efficacy of photodynamic therapy for bacterial biofilm infections …

Recent development of nanozymes for combating bacterial drug resistance: a review

L **e, H Wu, Y Li, L Shi, Y Liu - Advanced Healthcare Materials, 2024 - Wiley Online Library
Abstract The World Health Organization has warned that without effective action, deaths
from drug‐resistant bacteria can exceed 10 million annually, making it the leading cause of …

Reaction‐Induced Self‐Assembly of Polymyxin Mitigates Cytotoxicity and Reverses Drug Resistance

X Hu, D Li, H Li, Y Piao, H Wan, T Zhou… - Advanced …, 2024 - Wiley Online Library
Polymyxins have been regarded as an efficient therapeutic against many life‐threatening,
multidrug resistant Gram‐negative bacterial infections; however, the cytotoxicity and …

A versatile hydrogel with antibacterial and sequential drug-releasing capability for the programmable healing of infectious keratitis

S Meng, H Hu, Y Qiao, F Wang, BN Zhang, D Sun… - ACS …, 2023 - ACS Publications
Hydrogels have attracted tremendous attention as favorable corneal substitutes for treating
severe infectious keratitis (IK). However, current hydrogel-based corneal substitutes were …

Reactive oxygen species-responsive pillararene-embedded covalent organic frameworks with amplified antimicrobial photodynamic therapy for the targeted …

S Liang, MH Li, ML Qi, H Hui, HP Zhang, J Zhou… - Nano Letters, 2024 - ACS Publications
Reactive oxygen species (ROS)-responsive drug delivery systems possess immense
potential for targeted delivery and controlled release of therapeutics. However, the rapid …

Magnetic Field‐Directed Deep Thermal Therapy via Double‐Layered Microneedle Patch for Promoting Tissue Regeneration in Infected Diabetic Skin Wounds

D He, X Liu, J Jia, B Peng, N Xu… - Advanced Functional …, 2024 - Wiley Online Library
Although near‐infrared (NIR) light‐based photothermal therapies have shown therapeutic
potential for infected wounds, the attenuation of NIR light intensity in tissue has severely …

Ellagic acid-modified gold nanoparticles to combat multi-drug resistant bacterial infections in vitro and in vivo

Y Wang, F Wu, Y Li, S Wang, Y Ren, L Shi… - Materials …, 2024 - pubs.rsc.org
The overuse of antibiotics has led to the rapid development of multi-drug resistant bacteria,
making antibiotics increasingly ineffective against bacterial infections. Consequently, there …

One-component lipidic bicontinuous nanospheres as a smart drug loading platform to eradicate candida biofilms in oral and vaginal infection

YZ Piao, L Su, X Hu, W He, X Hu, CA Omolo… - Nano Today, 2024 - Elsevier
Bicontinuous nanospheres (BCNs) with a highly twisted network of hydrophobic phases
interwoven with a network of hydrated hydrophilic parts are essential for the loading and …

Microenvironment‐adaptive nanodecoy synergizes bacterial eradication, inflammation alleviation, and immunomodulation in promoting biofilm‐associated diabetic …

L Chen, M Peng, W He, X Hu, J **ao, L Shi, Y Liu… - …, 2024 - Wiley Online Library
The presence of bacterial biofilms and the occurrence of excessive inflammatory response
greatly imped the healing process of chronic wounds in diabetic patients. However, effective …