Several challenges to current views of thalamocortical processing are offered here.
Glutamatergic pathways in thalamus and cortex are divided into two distinct classes: driver …

This paper considers psychotic symptoms in terms of false inferences or beliefs. It is based
on the notion that the brain is an inference machine that actively constructs hypotheses to …

The primary somatosensory (S1) and primary motor (M1) cortices are reciprocally
connected, and their interaction has long been hypothesized to contribute to coordinated …

Multiple cortical areas contribute to visual processing in mice. However, the functional
organization and development of higher visual areas are unclear. Here we used intrinsic …

The cholinergic system is a potent neuromodulatory system that plays critical roles in cortical
plasticity, attention and learning. In this review, we propose that the cellular effects of …

Metabotropic glutamate receptors (mGluRs) are found throughout thalamus and cortex and
are clearly important to circuit behavior in both structures, and so considering only …

Group II metabotropic glutamate receptor (mGluR) ligands are potential novel drugs for
neurological and psychiatric disorders, but little is known about the effects of these …

Somatosensory information is thought to arrive in thalamus through two glutamatergic routes
called the lemniscal and paralemniscal pathways via the ventral posterior medial (VPm) and …

Auditory cortex (AC) layer 5B (L5B) contains both corticocollicular neurons, a type of
pyramidal-tract neuron projecting to the inferior colliculus, and corticocallosal neurons, a …

Dynamic binding of different brain areas is critical for various cognitive functions. The
thalamic reticular nucleus (TRN) is a GABAergic nucleus that constrains information flow …