Recent trends and perspectives of artificial intelligence-based machine learning from discovery to manufacturing in biopharmaceutical industry

R Maharjan, JC Lee, K Lee, HK Han, KH Kim… - Journal of …, 2023 - Springer
Background Machine learning (ML) tools have become invaluable in potential drug
candidate screening, formulation development, manufacturing, and characterization of …

State-of-the-art review of neural network applications in pharmaceutical manufacturing: current state and future directions

E Gholipour, A Bastas - Journal of Intelligent Manufacturing, 2024 - Springer
Neural network applications, as an emerging machine learning technology, are increasingly
being integrated into pharmaceutical manufacturing technologies, offering significant …

[HTML][HTML] Appropriate budget contingency determination for construction projects: State-of-the-art

T Ammar, M Abdel-Monem, K El-Dash - Alexandria Engineering Journal, 2023 - Elsevier
Contingency is a critical component in the cost estimation process for any construction
project. The contingency reserve considers potential costs related to risks and uncertainties …

[HTML][HTML] An artificial neural network-particle swarm optimization (ANN-PSO) approach to predict the aeration efficiency of venturi aeration system

A Yadav, SM Roy - Smart Agricultural Technology, 2023 - Elsevier
In the present study, the artificial neural network-particle swarm optimization (ANN-PSO)
approach was adopted for optimizing the standard aeration efficiency (SAE) of the venturi …

[HTML][HTML] Interpretable artificial neural networks for retrospective QbD of pharmaceutical tablet manufacturing based on a pilot-scale developmental dataset

B Nagy, Á Szabados-Nacsa, G Fülöp… - International Journal of …, 2023 - Elsevier
As the pharmaceutical industry increasingly adopts the Pharma 4.0. concept, there is a
growing need to effectively predict the product quality based on manufacturing or in-process …

Serial artificial neural networks characterized by Gaussian mixture for the modelling of the Consigma25 continuous manufacturing line

AA Wafa'H, M Mahfouf, C Omar, RB Al-Asady… - Powder Technology, 2024 - Elsevier
In this research, the Consigma25 Continuous Manufacturing (CM) Line is statistically
analysed and modelled. First, the main effects plot is employed to examine the effects of …

[HTML][HTML] Explainable deep recurrent neural networks for the batch analysis of a pharmaceutical tableting process in the spirit of Pharma 4.0

B Honti, A Farkas, ZK Nagy, H Pataki, B Nagy - International Journal of …, 2024 - Elsevier
Due to the continuously increasing Cost of Goods Sold, the pharmaceutical industry has
faced several challenges, and the Right First-Time principle with data-driven decision …

Comparing the performance of Raman and near-infrared imaging in the prediction of the in vitro dissolution profile of extended-release tablets based on artificial …

DL Galata, S Gergely, R Nagy, J Slezsák, F Ronkay… - Pharmaceuticals, 2023 - mdpi.com
In this work, the performance of two fast chemical imaging techniques, Raman and near-
infrared (NIR) imaging is compared by utilizing these methods to predict the rate of drug …

Enantioselective nanofiltration using predictive process modeling: Bridging the gap between materials development and process requirements

AK Beke, G Szekely - Journal of Membrane Science, 2022 - Elsevier
Organic solvent nanofiltration (OSN) is a low-energy alternative for continuous separations
in the chemical industry. As the pharmaceutical sector increasingly turns toward continuous …

Magnetic impacts on double diffusion of a non‐Newtonian NEPCM in a grooved cavity: ANN model with ISPH simulations

N Alsedias, AM Aly - Heat Transfer, 2024 - Wiley Online Library
Employing phase change materials (PCMs) offers the advantage of storing and releasing
thermal energy while ensuring temperature stability. This characteristic makes PCMs …