Retinal ganglion cells (RGCs) are the bridging neurons that connect the retinal input to the
visual processing centres within the central nervous system. There is a remarkable diversity …

Glaucoma is a group of diseases characterized by progressive optic nerve degeneration that
results in visual field loss and irreversible blindness. A crucial element in the …

Retinal ganglion cell (RGC) death in glaucoma and other optic neuropathies results in
irreversible vision loss due to the mammalian central nervous system's limited regenerative …

Retinal ganglion cell (RGC) loss is a hallmark of glaucoma and the second leading cause of
blindness worldwide. The type and timing of cellular changes leading to RGC loss in …

Glaucoma is a complex neurodegenerative disorder that is expected to affect 80 million
people by the end of this decade. Retinal ganglion cells (RGCs) are the most affected cell …

Glaucoma is characterized by retinal ganglion cell (RGC) pathology and a progressive loss
of vision. Previous studies suggest RGC death is responsible for vision loss in glaucoma, yet …

Background Glaucoma is a complex, multifactorial disease characterised by the loss of
retinal ganglion cells and their axons leading to a decrease in visual function. The earliest …

Using a variety of double and triple labeling techniques, we have reevaluated the death of
retinal neurons in a mouse model of hereditary glaucoma. Cell-specific markers and total …

Glaucoma, the second leading cause of blindness, is characterized by changes in the optic
disc and visual field defects. The elevated intraocular pressure was considered the prime …

Key issues concerning ganglion cell type-specific loss and synaptic changes in animal
models of experimental glaucoma remain highly debated. Importantly, changes in the …