Recent advances in ionic liquids in biomedicine

AM Curreri, S Mitragotri, EEL Tanner - Advanced Science, 2021 - Wiley Online Library
The use of ionic liquids and deep eutectic solvents in biomedical applications has grown
dramatically in recent years due to their unique properties and their inherent tunability. This …

[HTML][HTML] The role of ionic liquids in the pharmaceutical field: An overview of relevant applications

SN Pedro, CS R. Freire, AJD Silvestre… - International journal of …, 2020 - mdpi.com
Solubility, bioavailability, permeation, polymorphism, and stability concerns associated to
solid-state pharmaceuticals demand for effective solutions. To overcome some of these …

Toward the proactive design of sustainable chemicals: Ionic liquids as a prime example

S Beil, M Markiewicz, CS Pereira, P Stepnowski… - Chemical …, 2021 - ACS Publications
The tailorable and often unique properties of ionic liquids (ILs) drive their implementation
into a broad variety of seminal technologies. The modular design of ILs allows in this context …

Mechanisms of action of ionic liquids on living cells: The state of the art

P Kumari, VVS Pillai, A Benedetto - Biophysical reviews, 2020 - Springer
Ionic liquids (ILs) are a relatively new class of organic electrolytes composed of an organic
cation and either an organic or inorganic anion, whose melting temperature falls around …

[HTML][HTML] Ionic liquids as potential and synergistic permeation enhancers for transdermal drug delivery

Z Sidat, T Marimuthu, P Kumar, LC du Toit… - Pharmaceutics, 2019 - mdpi.com
Transdermal drug delivery systems (TDDS) show clear advantages over conventional routes
of drug administration. Nonetheless, there are limitations to current TDDS which warrant …

Room temperature ionic liquids meet biomolecules: a microscopic view of structure and dynamics

A Benedetto, P Ballone - ACS Sustainable Chemistry & …, 2016 - ACS Publications
Room temperature ionic liquids (RTILs) and biomolecules are both paradigmatic classes of
organic molecules, each consisting of a prodigious number of distinct chemical species …

Ionic liquids meet lipid bilayers: A state-of-the-art review

A Benedetto - Biophysical Reviews, 2023 - Springer
In the past 25 years, a vast family of complex organic salts known as room-temperature ionic
liquids (ILs) has received increasing attention due to their potential applications. ILs are …

[HTML][HTML] Imidazolium-based ionic liquids cause mammalian cell death due to modulated structures and dynamics of cellular membrane

K Bakshi, S Mitra, VK Sharma, MSK Jayadev… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Here, we report the toxic effects of various imidazolium-based ionic liquids (ILs) with varying
hydrocarbon chain lengths, on different human cell lines. Multiple biological assays have …

A review on (eco) toxicity of ionic liquids and their interaction with phospholipid membranes

N Kaur, VS Mithu, S Kumar - Journal of Molecular Liquids, 2024 - Elsevier
Ionic liquids (ILs) are salt-like organic compounds that are composed of organic cations and
organic/inorganic anions. The constituting ions play a crucial role in dictating their …

Choline-amino acid ionic liquids: past and recent achievements about the structure and properties of these really “green” chemicals

L Gontrani - Biophysical reviews, 2018 - Springer
The structure of choline-amino acid ionic liquids, atoxic task-specific solvents composed of
materials originated from renewable feedstocks, is reviewed in this letter. The varied and …