The function of many biological systems, such as embryos, liver lobules, intestinal villi, and
tumors, depends on the spatial organization of their cells. In the past decade, high …

The rapid and enthusiastic adoption of single-cell RNA sequencing (scRNA-seq) has
demonstrated that this technology is far more than just another way to perform transcriptome …

Many spatially resolved transcriptomic technologies do not have single-cell resolution but
measure the average gene expression for each spot from a mixture of cells of potentially …

Liver metastasis, the leading cause of colorectal cancer mortality, exhibits a highly
heterogeneous and suppressive immune microenvironment. Here, we sequenced 97 …

Although complex inflammatory-like alterations are observed around the amyloid plaques of
Alzheimer's disease (AD), little is known about the molecular changes and cellular …

A limitation of spatial transcriptomics technologies is that individual measurements may
contain contributions from multiple cells, hindering the discovery of cell-type-specific spatial …

Charting an organs' biological atlas requires us to spatially resolve the entire single-cell
transcriptome, and to relate such cellular features to the anatomical scale. Single-cell and …

Spatial transcriptomics are a collection of genomic technologies that have enabled
transcriptomic profiling on tissues with spatial localization information. Analyzing spatial …

Recent development of spatial transcriptomics (ST) is capable of associating spatial
information at different spots in the tissue section with RNA abundance of cells within each …

Single-cell RNA-sequencing (scRNA-seq) technologies have revolutionized modern
biomedical sciences. A fundamental challenge is to incorporate spatial information to study …