MicroRNA delivery through nanoparticles

SWL Lee, C Paoletti, M Campisi, T Osaki… - Journal of Controlled …, 2019 - Elsevier
MicroRNAs (miRNAs) are attracting a growing interest in the scientific community due to
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …

A review of microRNA biomarkers in traumatic brain injury

H Atif, SD Hicks - Journal of experimental neuroscience, 2019 - journals.sagepub.com
There is growing public concern surrounding traumatic brain injury (TBI). TBI can cause
significant morbidity, and the long-term sequelae are poorly understood. TBI diagnosis and …

How alcohol drinking affects our genes: An epigenetic point of view

S Ciafrè, V Carito, G Ferraguti, A Greco… - … and Cell Biology, 2019 - cdnsciencepub.com
This work highlights recent studies in epigenetic mechanisms that play a role in alcoholism,
which is a complex multifactorial disorder. There is a large body of evidence showing that …

Comparison of serum and saliva miRNAs for identification and characterization of mTBI in adult mixed martial arts fighters

D LaRocca, S Barns, SD Hicks, A Brindle, J Williams… - PloS one, 2019 - journals.plos.org
Traumatic brain injury (TBI) is a major cause of death and disability worldwide, with mild TBI
(mTBI) accounting for 85% of cases. mTBI is also implicated in serious long-term sequelae …

MicroRNAs in drug addiction: Current status and future perspectives

Y Zhao, F Qin, S Han, S Li, Y Zhao, H Wang… - Pharmacology & …, 2022 - Elsevier
Drug addiction is a chronic and relapsing brain disorder characterized by compulsive drug
seeking and continued drug use despite adverse consequences. The high prevalence and …

MiRNA differences related to treatment-resistant schizophrenia

D Pérez-Rodríguez, MA Penedo… - International journal of …, 2023 - mdpi.com
Schizophrenia (SZ) is a serious mental disorder that is typically treated with antipsychotic
medication. Treatment-resistant schizophrenia (TRS) is the condition where symptoms …

Blood biomarkers for assessment of mild traumatic brain injury and chronic traumatic encephalopathy

MI Hiskens, AG Schneiders, M Angoa-Pérez… - Biomarkers, 2020 - Taylor & Francis
Mild traumatic brain injuries (mTBI) are prevalent and can result in significant debilitation.
Current diagnostic methods have implicit limitations, with clinical assessment tools reliant on …

[HTML][HTML] An insight into miR-1290: an oncogenic miRNA with diagnostic potential

M Guz, W Jeleniewicz, M Cybulski - International Journal of Molecular …, 2022 - mdpi.com
For more than two decades, the view of the roles of non-coding RNAs (ncRNAs) has been
radically changing. These RNA molecules that are transcribed from our genome do not have …

Neuron enriched extracellular vesicles' MicroRNA expression profiles as a marker of early life alcohol consumption

V Yakovlev, DM Lapato, P Rana, P Ghosh… - Translational …, 2024 - nature.com
Alcohol consumption may impact and shape brain development through perturbed
biological pathways and impaired molecular functions. We investigated the relationship …

Epigenetic modification in alcohol use disorder and alcoholic cardiomyopathy: from pathophysiology to therapeutic opportunities

L Wu, Y Zhang, J Ren - Metabolism, 2021 - Elsevier
Alcohol consumption prompts detrimental psychological, pathophysiological and health
issues, representing one of the major causes of death worldwide. Alcohol use disorder …