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Discovering riboswitches: the past and the future
Riboswitches are structured noncoding RNA domains used by many bacteria to monitor the
concentrations of target ligands and regulate gene expression accordingly. In the past 20 …
concentrations of target ligands and regulate gene expression accordingly. In the past 20 …
Photocleavable Ortho-Nitrobenzyl-Protected DNA Architectures and Their Applications
This review article introduces mechanistic aspects and applications of photochemically
deprotected ortho-nitrobenzyl (ONB)-functionalized nucleic acids and their impact on …
deprotected ortho-nitrobenzyl (ONB)-functionalized nucleic acids and their impact on …
Reptile Search Algorithm (RSA): A nature-inspired meta-heuristic optimizer
This paper proposes a novel nature-inspired meta-heuristic optimizer, called Reptile Search
Algorithm (RSA), motivated by the hunting behaviour of Crocodiles. Two main steps of …
Algorithm (RSA), motivated by the hunting behaviour of Crocodiles. Two main steps of …
Stimuli-responsive metal–organic framework nanoparticles for controlled drug delivery and medical applications
Stimuli-responsive metal–organic framework nanoparticles, NMOFs, provide a versatile
platform for the controlled release of drugs and biomedical applications. The porous …
platform for the controlled release of drugs and biomedical applications. The porous …
A functional group–guided approach to aptamers for small molecules
K Yang, NM Mitchell, S Banerjee, Z Cheng, S Taylor… - Science, 2023 - science.org
Aptameric receptors are important biosensor components, yet our ability to identify them
depends on the target structures. We analyzed the contributions of individual functional …
depends on the target structures. We analyzed the contributions of individual functional …
Self-assembling nucleic acid nanostructures functionalized with aptamers
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …
would allow artificial biopolymer complexes to self-assemble and function similarly to the …
Evolution of dip-pen nanolithography (DPN): from molecular patterning to materials discovery
Dip-pen nanolithography (DPN) is a nanofabrication technique that can be used to directly
write molecular patterns on substrates with high resolution and registration. Over the past …
write molecular patterns on substrates with high resolution and registration. Over the past …
Aptamer-based biosensors for biomedical diagnostics
Aptamers are single-stranded nucleic acids that selectively bind to target molecules. Most
aptamers are obtained through a combinatorial biology technique called SELEX. Since …
aptamers are obtained through a combinatorial biology technique called SELEX. Since …
Nano‐sized CT contrast agents
Computed tomography (CT) is one of the most widely used clinical imaging modalities. In
order to increase the sensitivity of CT, small iodinated compounds are used as injectable …
order to increase the sensitivity of CT, small iodinated compounds are used as injectable …
[HTML][HTML] From cascaded catalytic nucleic acids to enzyme–DNA nanostructures: controlling reactivity, sensing, logic operations, and assembly of complex structures
DNA is one of the most fascinating biopolymers. Besides its central role as carrier of genetic
information and translation of the genetic code into proteins, DNA holds great promise as a …
information and translation of the genetic code into proteins, DNA holds great promise as a …