Transcranial focused ultrasound neuromodulation: a review of the excitatory and inhibitory effects on brain activity in human and animals

T Zhang, N Pan, Y Wang, C Liu, S Hu - Frontiers in Human …, 2021 - frontiersin.org
Non-invasive neuromodulation technology is important for the treatment of brain diseases.
The effects of focused ultrasound on neuronal activity have been investigated since the …

A review of functional brain differences predicting relapse in substance use disorder: Actionable targets for new methods of noninvasive brain stimulation

BC Gibson, ED Claus, J Sanguinetti… - Neuroscience & …, 2022 - Elsevier
Neuroimaging studies have identified a variety of brain regions whose activity predicts
substance use (ie, relapse) in patients with substance use disorder (SUD), suggesting that …

[HTML][HTML] Noninvasive ultrasound deep brain stimulation for the treatment of Parkinson's disease model mouse

H Zhou, L Niu, L Meng, Z Lin, J Zou, X **a, X Huang… - Research, 2019 - spj.science.org
Modulating basal ganglia circuitry is of great significance in the improvement of motor
function in Parkinson's disease (PD). Here, for the first time, we demonstrate that …

[HTML][HTML] Noninvasive ultrasound stimulation of ventral tegmental area induces reanimation from general anaesthesia in mice

T Bian, W Meng, M Qiu, Z Zhong, Z Lin, J Zou, Y Wang… - Research, 2021 - spj.science.org
Evidence in animals suggests that deep brain stimulation or optogenetics can be used for
recovery from disorders of consciousness (DOC). However, these treatments require …

LIPUS regulates the progression of knee osteoarthritis in mice through primary cilia-mediated TRPV4 channels

S Wu, H Zhou, H Ling, Y Sun, Z Luo, TN Ngo, Y Fu… - Apoptosis, 2024 - Springer
Osteoarthritis (OA) is a common disease in middle-aged and elderly people. An imbalance
in calcium ion homeostasis will contribute to chondrocyte apoptosis and ultimately lead to …

A Bibliometric Analysis for Low‐Intensity Ultrasound Study Over the Past Three Decades

H Chang, Q Wang, T Liu, L Chen… - … of Ultrasound in …, 2023 - Wiley Online Library
Low‐intensity ultrasound (LI‐US) is a non‐invasive stimulation technique that has emerged
in recent years and has been shown to have positive effects on neuromodulation, fracture …

Therapeutic potential of ultrasound neuromodulation in decreasing neuropathic pain: clinical and experimental evidence

I Pérez-Neri, A González-Aguilar… - Current …, 2021 - ingentaconnect.com
Background: For more than seven decades, ultrasound has been used as an imaging and
diagnostic tool. Today, new technologies, such as focused ultrasound (FUS) …

Ultrasound stimulation of periaqueductal gray induces defensive behaviors

Y Wang, L Niu, W Meng, Z Lin, J Zou… - IEEE transactions on …, 2020 - ieeexplore.ieee.org
Low-intensity focused ultrasound stimulation (LIFUS) has the potential to noninvasively
penetrate the intact skull and to modulate neural activity in the cortex and deep brain nuclei …

Advances in transcranial focused ultrasound neuromodulation for mental disorders

Y Shi, W Wu - Progress in Neuro-Psychopharmacology and …, 2025 - Elsevier
Mental disorders are a major public health concern, affecting millions worldwide. Current
treatments have limitations, highlighting the need for novel, effective, and safe interventions …

Transcranial low-intensity pulsed ultrasound stimulation induces neuronal autophagy

X Huang, L Niu, L Meng, Z Lin, W Zhou… - IEEE Transactions …, 2020 - ieeexplore.ieee.org
Autophagy, or cellular self-digestion, is an essential process for eliminating abnormal
protein in mammalian cells. Accumulating evidence indicates that increased neuronal …