Glutamate is the primary excitatory neurotransmitter in the central nervous system (CNS)
which initiates rapid signal transmission in the synapse before its re-uptake into the …

Manganese (Mn) is an essential micronutrient required for the normal development of many
organs, including the brain. Although its roles as a cofactor in several enzymes and in …

Exposure to manganese (Mn) causes clinical signs and symptoms resembling, but not
identical to, Parkinson's disease. Since our last review on this subject in 2004, the past …

Abstract Manganese-based Metal-organic Frameworks (Mn-MOFs) represents a unique sub-
class of MOFs with low toxicity, oxidative ability, and biocompatibility, which plays vital role in …

Although manganese is an essential trace metal, little is known about its transport and
homeostatic regulation. Here we have identified a cohort of patients with a novel autosomal …

Nanomaterials have the potential to improve how patients are clinically treated and
diagnosed. While there are a number of nanomaterials that can be used toward improved …

Impaired cellular homeostasis of metals, particularly of Cu, Fe and Mn may trigger
neurodegeneration through various mechanisms, notably induction of oxidative stress …

Congenital portosystemic shunts are present in one in 30,000 children. Among the
associated risks of severe complications are neonatal cholestasis, benign and malignant …

Manganese (Mn) is an essential trace metal that is pivotal for normal cell function and
metabolism. Its homeostasis is tightly regulated; however, the mechanisms of Mn …

Chronic, sustained inflammation underlies many pathological conditions, including
neurodegenerative diseases. Divalent manganese (Mn2+) exposure can stimulate …