Quaternary ammonium-based biomedical materials: State-of-the-art, toxicological aspects and antimicrobial resistance

Y Jiao, L Niu, S Ma, J Li, FR Tay, J Chen - Progress in polymer science, 2017 - Elsevier
Microbial infections affect humans worldwide. Many quaternary ammonium compounds
have been synthesized that are not only antibacterial, but also possess antifungal, antiviral …

The implication of probiotics in the prevention of dental caries

TH Lin, CH Lin, TM Pan - Applied microbiology and biotechnology, 2018 - Springer
The current oral health crisis, whose causes are varied and complex, necessitates timely
oral evaluation and early detection and treatment of oral health problems. Dramatic changes …

Cross-feeding and interkingdom communication in dual-species biofilms of Streptococcus mutans and Candida albicans

H Sztajer, SP Szafranski, J Tomasch, M Reck… - The ISME …, 2014 - academic.oup.com
Polymicrobial biofilms are of large medical importance, but relatively little is known about the
role of interspecies interactions for their physiology and virulence. Here, we studied two …

Cyclic di‐AMP mediates biofilm formation

X Peng, Y Zhang, G Bai, X Zhou… - Molecular microbiology, 2016 - Wiley Online Library
Cyclic di‐AMP (c‐di‐AMP) is an emerging second messenger in bacteria. It has been shown
to play important roles in bacterial fitness and virulence. However, transduction of c‐di‐AMP …

Regulation of competence for natural transformation in streptococci

L Fontaine, A Wahl, M Fléchard, J Mignolet… - Infection, Genetics and …, 2015 - Elsevier
Natural DNA transformation is a lateral gene transfer mechanism during which bacteria take
up naked DNA from their environment and stably integrate it in their genome. The proteins …

Community interactions of oral streptococci

NS Jakubovics, SA Yassin, AH Rickard - Advances in applied microbiology, 2014 - Elsevier
It is now clear that the most common oral diseases, dental caries and periodontitis, are
caused by mixed-species communities rather than by individual pathogens working in …

Comprehensive analysis of bacteriocins in Streptococcus mutans

A Watanabe, M Kawada-Matsuo, MNT Le… - Scientific reports, 2021 - nature.com
Streptococcus mutans produces bacteriocins that show antibacterial activity against several
bacteria. However, comprehensive analysis of these bacteriocins has not been well done. In …

Development of the oral resistome during the first decade of life

S Sukumar, F Wang, CA Simpson, CE Willet… - Nature …, 2023 - nature.com
Antibiotic overuse has promoted the spread of antimicrobial resistance (AMR) with
significant health and economic consequences. Genome sequencing reveals the …

The vicK gene of Streptococcus mutans mediates its cariogenicity via exopolysaccharides metabolism

Y Deng, Y Yang, B Zhang, H Chen, Y Lu… - International Journal of …, 2021 - nature.com
Streptococcus mutans (S. mutans) is generally regarded as a major contributor to dental
caries because of its ability to synthesize extracellular polysaccharides (EPS) that aid in the …

Multi-targeted antisense oligonucleotide delivery by a framework nucleic acid for inhibiting biofilm formation and virulence

Y Zhang, X **e, W Ma, Y Zhan, C Mao, X Shao, Y Lin - Nano-micro letters, 2020 - Springer
Biofilm formation is responsible for numerous chronic infections and represents a serious
health challenge. Bacteria and the extracellular polysaccharides (EPS) cause biofilms to …