The extracellular matrix (ECM) establishes the basis for the cell's microenvironment
providing structural and mechanical support to cells and tissues, and regulating multiple cell …

There is growing appreciation of the importance of the mechanical properties of the tumor
microenvironment on disease progression. However, the role of extracellular matrix (ECM) …

Many cells are small and rounded on soft extracellular matrices (ECM), elongated on stiffer
ECMs, and flattened on hard ECMs. Cells also migrate up stiffness gradients (durotaxis) …

The self-organization of cells into complex tissues during growth and regeneration is a
combination of physical–mechanical events and biochemical signal processing. Cells …

Cancer cell migration is a widely studied topic but has been very often limited to two
dimensional motion on various substrates. Indeed, less is known about cancer cell migration …

The distribution and location of mast cells are closely related to their physiological and
pathological functions, such as allergic responses, immunity, and fibrosis, and are used in …

The effect of extracellular matrix (ECM) stiffness on embryonic trophoblast cells invasion
during mammalian embryo implantation remains largely unknown. In this study, we …

Cellular transformation owing to cigarette smoking is due to chronic exposure and not acute.
However, systematic studies to understand the molecular alterations in lung cells due to …

Engineering interfaces of distinct extracellular compartments mimicking native tissues are
key for in-depth in vitro studies on developmental and disease processes in biology and …

Regenerative medicine is one of the most promising future approaches for the treatment of
damaged tissues and organs. Its methodologies are based on a good understanding and …