Macrophages are critically involved in wound healing, from dampening inflammation to
clearing cell debris and coordinating tissue repair. Within the wound, the complexity of …

Idiopathic pulmonary fibrosis (IPF) is a prototype of lethal, chronic, progressive interstitial
lung disease of unknown etiology. Over the past decade, macrophage has been recognized …

m6A RNA modification is implicated in multiple cellular responses. However, its function in
the innate immune cells is poorly understood. Here, we identified major m6A “writers” as the …

Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pulmonary
disease with a median survival of 2–4 years after diagnosis. A significant number of IPF …

Senescence of alveolar type II (ATII) cells, progenitors of the alveolar epithelium, is a
pathological feature and contributes importantly to the pathogenesis of idiopathic pulmonary …

Oxidative stress has been linked to various disease states as well as physiological aging.
The lungs are uniquely exposed to a highly oxidizing environment and have evolved several …

Innate immune signaling plays an important role in inflammation, and dysregulation of
signaling components within this pathway has been focused as a critical mediator in …

Fibrosis and pneumonitis are the most important side effects of lung tissue following cancer
therapy. Radiotherapy and chemotherapy by some drugs, such as bleomycin, can induce …

Idiopathic pulmonary fibrosis (IPF) is a highly lethal pathological process that is
characterized by inflammation, fibroblast accumulation, and excessive collagen deposition …

Idiopathic pulmonary fibrosis (IPF) is defined as a specific form of chronic, progressive
fibrosing interstitial pneumonia of unknown cause and limited to the lungs. Schisandrae …