Critical illness weakness, polyneuropathy and myopathy: diagnosis, treatment, and long-term outcomes

N Latronico, FA Rasulo, M Eikermann, S Piva - Critical Care, 2023 - Springer
Background Severe weakness associated with critical illness (CIW) is common. This
narrative review summarizes the latest scientific insights and proposes a guide for clinicians …

Detecting awareness after acute brain injury

K Kazazian, BL Edlow, AM Owen - The Lancet Neurology, 2024 - thelancet.com
Advances over the past two decades in functional neuroimaging have provided new
diagnostic and prognostic tools for patients with severe brain injury. Some of the most …

Critical dynamics in spontaneous EEG predict anesthetic-induced loss of consciousness and perturbational complexity

C Maschke, J O'Byrne, MA Colombo, M Boly… - Communications …, 2024 - nature.com
Consciousness has been proposed to be supported by electrophysiological patterns poised
at criticality, a dynamical regime which exhibits adaptive computational properties …

Covert cortical processing: a diagnosis in search of a definition

MJ Young, M Fecchio, YG Bodien… - Neuroscience of …, 2024 - academic.oup.com
Historically, clinical evaluation of unresponsive patients following brain injury has relied
principally on serial behavioral examination to search for emerging signs of consciousness …

Common data elements for disorders of consciousness: recommendations from the electrophysiology working group

EE Carroll, C Der-Nigoghossian, A Alkhachroum… - Neurocritical care, 2023 - Springer
Background Electroencephalography (EEG) has long been recognized as an important tool
in the investigation of disorders of consciousness (DoC). From inspection of the raw EEG to …

Functional near-infrared spectroscopy: A novel tool for detecting consciousness after acute severe brain injury

K Kazazian, A Abdalmalak, SL Novi, L Norton… - Proceedings of the …, 2024 - pnas.org
Recent advancements in functional neuroimaging have demonstrated that some
unresponsive patients in the intensive care unit retain a level of consciousness that is …

Disclosing results of tests for covert consciousness: A framework for ethical translation

MJ Young, K Kazazian, D Fischer, IA Lissak… - Neurocritical Care, 2024 - Springer
The advent of neurotechnologies including advanced functional magnetic resonance
imaging and electroencephalography to detect states of awareness not detectable by …

Autonomic nervous system modulation during self-induced non-ordinary states of consciousness

V Oswald, A Vanhaudenhuyse, J Annen, C Martial… - Scientific Reports, 2023 - nature.com
Self-induced cognitive trance (SICT) is a voluntary non-ordinary state of consciousness
characterized by a lucid yet narrowed awareness of the external surroundings. It involves a …

Disorders of consciousness rehabilitation: Ethical dimensions and epistemic dilemmas

MJ Young - Physical Medicine and Rehabilitation Clinics, 2024 - pmr.theclinics.com
Patients with disorders of consciousness (DoC) who survive to discharge following severe
brain injury can face profoundly complex medical, ethical, and psychosocial challenges …

International survey on the implementation of the European and American guidelines on disorders of consciousness

M Farisco, R Formisano, O Gosseries, Y Kato… - Journal of …, 2024 - Springer
Diagnostic, prognostic, and therapeutic procedures for patients with prolonged disorders of
consciousness (pDoCs) vary significantly across countries and clinical settings, likely due to …