Advances in biosynthesis, regulation, and metabolic engineering of plant specialized terpenoids

DA Nagegowda, P Gupta - Plant Science, 2020 - Elsevier
Plant specialized terpenoids are natural products that have no obvious role in growth and
development, but play many important functional roles to improve the plant's overall fitness …

Bioactivities, biosynthesis and biotechnological production of phenolic acids in Salvia miltiorrhiza

M Shi, F Huang, C Deng, Y Wang… - Critical reviews in food …, 2019 - Taylor & Francis
ABSTRACT Salvia miltiorrhiza (Danshen in Chinese), is a well-known traditional Chinese
medicinal plant, which is used as not only human medicine but also health-promotion food …

Danshen: a phytochemical and pharmacological overview

XD MEIm, C Yan-Feng, C Yan-Yun, LI **g… - Chinese Journal of …, 2019 - Elsevier
Danshen, the dried root or rhizome of Salvia miltiorrhiza Bge., is a traditional and folk
medicine in Asian countries, especially in China and Japan. In this review, we summarized …

The potential of the mevalonate pathway for enhanced isoprenoid production

P Liao, A Hemmerlin, TJ Bach, ML Chye - Biotechnology advances, 2016 - Elsevier
The cytosol-localised mevalonic acid (MVA) pathway delivers the basic isoprene unit
isopentenyl diphosphate (IPP). In higher plants, this central metabolic intermediate is also …

Tanshinones, Critical Pharmacological Components in Salvia miltiorrhiza

Z Jiang, W Gao, L Huang - Frontiers in Pharmacology, 2019 - frontiersin.org
Salvia miltiorrhiza Bunge, a member of the Lamiaceae family, is valued in traditional
Chinese Medicine. Its dried root (named Danshen) has been used for hundreds of years …

Molecular regulation of the key specialized metabolism pathways in medicinal plants

M Shi, S Zhang, Z Zheng, I Maoz… - Journal of Integrative …, 2024 - Wiley Online Library
The basis of modern pharmacology is the human ability to exploit the production of
specialized metabolites from medical plants, for example, terpenoids, alkaloids, and …

Modular pathway engineering of diterpenoid synthases and the mevalonic acid pathway for miltiradiene production

YJ Zhou, W Gao, Q Rong, G **, H Chu… - Journal of the …, 2012 - ACS Publications
Microbial production can be advantageous over the extraction of phytoterpenoids from
natural plant sources, but it remains challenging to rationally and rapidly access efficient …

[HTML][HTML] Tanshinone and salvianolic acid biosynthesis are regulated by SmMYB98 in Salvia miltiorrhiza hairy roots

X Hao, Z Pu, G Cao, D You, Y Zhou, C Deng… - Journal of Advanced …, 2020 - Elsevier
Salvia miltiorrhiza Bunge is an herb rich in bioactive tanshinone and salvianolic acid
compounds. It is primarily used as an effective medicine for treating cardiovascular and …